Philipp Hilgendorf
Overview
Explore the profile of Philipp Hilgendorf including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
16
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0
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Recent Articles
1.
Yu Z, Sasidharan-Nair V, Buchta T, Bonifacius A, Khan F, Pietzsch B, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012581.
PMID: 39325839
Epigenetic mechanisms stabilize gene expression patterns during CD8+ T cell differentiation. Although adoptive transfer of virus-specific T cells is clinically applied to reduce the risk of virus infection or reactivation...
2.
Drost F, Dorigatti E, Straub A, Hilgendorf P, Wagner K, Heyer K, et al.
Cell Genom
. 2024 Aug;
4(9):100634.
PMID: 39151427
Cancer cells and pathogens can evade T cell receptors (TCRs) via mutations in immunogenic epitopes. TCR cross-reactivity (i.e., recognition of multiple epitopes with sequence similarities) can counteract such escape but...
3.
Winterhalter P, Warmuth L, Hilgendorf P, Schutz J, Dotsch S, Tonn T, et al.
Blood Adv
. 2024 Apr;
8(13):3416-3426.
PMID: 38640254
Adoptive cellular therapies have shown enormous potential but are complicated by personalization. Because of HLA mismatch, rejection of transferred T cells frequently occurs, compromising the T-cell graft's functionality. This obstacle...
4.
Straub A, Grassmann S, Jarosch S, Richter L, Hilgendorf P, Hammel M, et al.
Immunity
. 2023 May;
56(6):1269-1284.e6.
PMID: 37164014
Repetitive pathogen exposure leads to the dominant outgrowth of T cell clones with high T cell receptor (TCR) affinity to the relevant pathogen-associated antigens. However, low-affinity clones are also known...