Michael Beckstette
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Explore the profile of Michael Beckstette including associated specialties, affiliations and a list of published articles.
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43
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1837
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Recent Articles
1.
Yu Z, Sasidharan-Nair V, Buchta T, Bonifacius A, Khan F, Pietzsch B, et al.
PLoS Pathog
. 2024 Sep;
20(9):e1012581.
PMID: 39325839
Epigenetic mechanisms stabilize gene expression patterns during CD8+ T cell differentiation. Although adoptive transfer of virus-specific T cells is clinically applied to reduce the risk of virus infection or reactivation...
2.
Scholpp A, Schilbert H, Viehover P, Weisshaar B, Beckstette M, Neumann J, et al.
Front Plant Sci
. 2024 Sep;
15:1412189.
PMID: 39290728
, also knowen as the Japanese tea hortensia, is known for its sweet taste and health properties of bevarages produced from this plant. The 3,4-dihydroisocoumarins, hydrangenol and phyllodulcin harbour a...
3.
Meyer I, Volk M, Salto I, Moesser T, Chaoprasid P, Herbruggen A, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1011965.
PMID: 39159284
RNA degradation is an essential process that allows bacteria to regulate gene expression and has emerged as an important mechanism for controlling virulence. However, the individual contributions of RNases in...
4.
Zou M, Pezoldt J, Mohr J, Philipsen L, Leufgen A, Cerovic V, et al.
Cell Rep
. 2024 Apr;
43(5):114153.
PMID: 38687643
Gut-draining mesenteric and celiac lymph nodes (mLNs and celLNs) critically contribute to peripheral tolerance toward food and microbial antigens by supporting the de novo induction of regulatory T cells (Tregs)....
5.
Hassa J, Tubbesing T, Maus I, Heyer R, Benndorf D, Effenberger M, et al.
Microorganisms
. 2023 Oct;
11(10).
PMID: 37894070
The current focus on renewable energy in global policy highlights the importance of methane production from biomass through anaerobic digestion (AD). To improve biomass digestion while ensuring overall process stability,...
6.
Boldt J, Lukoseviciute L, Fu C, Steglich M, Bunk B, Junker V, et al.
Microb Biotechnol
. 2023 Mar;
16(5):1054-1068.
PMID: 36998231
A better understanding of the genetic regulation of the biosynthesis of microbial compounds could accelerate the discovery of new biologically active molecules and facilitate their production. To this end, we...
7.
Pezoldt J, Wiechers C, Zou M, Litovchenko M, Biocanin M, Beckstette M, et al.
Nat Commun
. 2022 Nov;
13(1):7227.
PMID: 36433946
Gut-draining mesenteric lymph nodes (LN) provide the framework to shape intestinal adaptive immune responses. Based on the transcriptional signatures established by our previous work, the composition and immunomodulatory function of...
8.
Beckstette M, Lu C, Herppich S, Diem E, Ntalli A, Ochel A, et al.
J Exp Med
. 2022 Aug;
219(10).
PMID: 35938981
Epigenetic modifications such as DNA methylation play an essential role in imprinting specific transcriptional patterns in cells. We performed genome-wide DNA methylation profiling of murine lymph node-derived ILCs, which led...
9.
Wiechers C, Pezoldt J, Beckstette M, Berner J, Schraml B, Huehn J
Immunology
. 2022 May;
166(4):475-491.
PMID: 35569092
Conventional dendritic cells (cDCs) arise from committed precursor dendritic cells (pre-DCs) in the bone marrow that continuously seed the periphery. Pre-DCs and other upstream progenitors proliferate and mature in response...
10.
Pezoldt J, Wiechers C, Erhard F, Rand U, Bulat T, Beckstette M, et al.
Commun Biol
. 2021 Dec;
4(1):1355.
PMID: 34857864
Our understanding of the composition and functions of splenic stromal cells remains incomplete. Here, based on analysis of over 20,000 single cell transcriptomes of splenic fibroblasts, we characterized the phenotypic...