Philipp Heuser
Overview
Explore the profile of Philipp Heuser including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
183
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Recent Articles
1.
Genthe E, Miletic S, Tekkali I, Hennell James R, Marlovits T, Heuser P
J Struct Biol
. 2023 Jun;
215(3):107990.
PMID: 37364763
Particle localization (picking) in digital tomograms is a laborious and time-intensive step in cryogenic electron tomography (cryoET) analysis often requiring considerable user involvement, thus becoming a bottleneck for automated cryoET...
2.
Agirre J, Atanasova M, Bagdonas H, Ballard C, Basle A, Beilsten-Edmands J, et al.
Acta Crystallogr D Struct Biol
. 2023 Jun;
79(Pt 6):449-461.
PMID: 37259835
The Collaborative Computational Project No. 4 (CCP4) is a UK-led international collective with a mission to develop, test, distribute and promote software for macromolecular crystallography. The CCP4 suite is a...
3.
Kruger D, Galli S, Zeller-Plumhoff B, Wieland D, Peruzzi N, Wiese B, et al.
Bioact Mater
. 2022 Feb;
13:37-52.
PMID: 35224290
Biodegradable magnesium (Mg) alloys can revolutionize osteosynthesis, because they have mechanical properties similar to those of the bone, and degrade over time, avoiding the need of removal surgery. However, they...
4.
Baltruschat I, Cwieka H, Kruger D, Zeller-Plumhoff B, Schlunzen F, Willumeit-Romer R, et al.
Sci Rep
. 2021 Dec;
11(1):24237.
PMID: 34930947
Highly accurate segmentation of large 3D volumes is a demanding task. Challenging applications like the segmentation of synchrotron radiation microtomograms (SRμCT) at high-resolution, which suffer from low contrast, high spatial...
5.
Han H, Round E, Schubert R, Gul Y, Makroczyova J, Meza D, et al.
J Appl Crystallogr
. 2021 Apr;
54(Pt 1):7-21.
PMID: 33833637
The science of X-ray free-electron lasers (XFELs) critically depends on the performance of the X-ray laser and on the quality of the samples placed into the X-ray beam. The stability...
6.
Chojnowski G, Sobolev E, Heuser P, Lamzin V
Acta Crystallogr D Struct Biol
. 2021 Feb;
77(Pt 2):142-150.
PMID: 33559604
Recent developments in cryogenic electron microscopy (cryo-EM) have enabled structural studies of large macromolecular complexes at resolutions previously only attainable using macromolecular crystallography. Although a number of methods can already...
7.
Morris C, Andreetto P, Banci L, Bonvin A, Chojnowski G, Del Cano L, et al.
J Struct Biol X
. 2020 Jul;
1:100006.
PMID: 32647812
The West-Life project (https://about.west-life.eu/) is a Horizon 2020 project funded by the European Commission to provide data processing and data management services for the international community of structural biologists, and...
8.
Chojnowski G, Choudhury K, Heuser P, Sobolev E, Pereira J, Oezugurel U, et al.
Acta Crystallogr D Struct Biol
. 2020 Mar;
76(Pt 3):248-260.
PMID: 32133989
The performance of automated protein model building usually decreases with resolution, mainly owing to the lower information content of the experimental data. This calls for a more elaborate use of...
9.
Heuser P, Langer G, Lamzin V
Acta Crystallogr D Biol Crystallogr
. 2009 Jul;
65(Pt 7):690-6.
PMID: 19564689
A novel approach to obtaining structural information from macromolecular X-ray data extending to resolutions as low as 20 A is presented. Following a simple map-segmentation procedure, the approximate shapes of...
10.
Heuser P, Schomburg D
BMC Bioinformatics
. 2007 Aug;
8:279.
PMID: 17678526
Background: Docking algorithms are developed to predict in which orientation two proteins are likely to bind under natural conditions. The currently used methods usually consist of a sampling step followed...