Philip S Robinson
Overview
Explore the profile of Philip S Robinson including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
350
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0
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Recent Articles
1.
Spencer Chapman M, Mitchell E, Yoshida K, Williams N, Fabre M, Ranzoni A, et al.
Nature
. 2025 Jan;
638(8051):729-738.
PMID: 39814886
DNA is subject to continual damage, leaving each cell with thousands of individual DNA lesions at any given moment. The efficiency of DNA repair means that most known classes of...
2.
Wang Y, Robinson P, Coorens T, Moore L, Lee-Six H, Noorani A, et al.
Nat Genet
. 2023 Jan;
55(2):246-254.
PMID: 36702998
APOBEC mutational signatures SBS2 and SBS13 are common in many human cancer types. However, there is an incomplete understanding of its stimulus, when it occurs in the progression from normal...
3.
Robinson P, Thomas L, Abascal F, Jung H, Harvey L, West H, et al.
Nat Commun
. 2022 Jul;
13(1):3949.
PMID: 35803914
Cellular DNA damage caused by reactive oxygen species is repaired by the base excision repair (BER) pathway which includes the DNA glycosylase MUTYH. Inherited biallelic MUTYH mutations cause predisposition to...
4.
Lee B, Robinson P, Coorens T, Yan H, Olafsson S, Lee-Six H, et al.
Nat Commun
. 2022 May;
13(1):2710.
PMID: 35581206
Lynch Syndrome (LS) is an autosomal dominant disease conferring a high risk of colorectal cancer due to germline heterozygous mutations in a DNA mismatch repair (MMR) gene. Although cancers in...
5.
Robinson P, Gasparetto M, Nowak J, Tel B, Strisciuglio C
J Pediatr Gastroenterol Nutr
. 2021 Nov;
74(4):e100.
PMID: 34724450
No abstract available.
6.
Robinson P, Coorens T, Palles C, Mitchell E, Abascal F, Olafsson S, et al.
Nat Genet
. 2021 Oct;
53(10):1434-1442.
PMID: 34594041
Mutation accumulation in somatic cells contributes to cancer development and is proposed as a cause of aging. DNA polymerases Pol ε and Pol δ replicate DNA during cell division. However,...
7.
Coorens T, Moore L, Robinson P, Sanghvi R, Christopher J, Hewinson J, et al.
Nature
. 2021 Aug;
597(7876):387-392.
PMID: 34433963
Starting from the zygote, all cells in the human body continuously acquire mutations. Mutations shared between different cells imply a common progenitor and are thus naturally occurring markers for lineage...
8.
Spencer Chapman M, Ranzoni A, Myers B, Williams N, Coorens T, Mitchell E, et al.
Nature
. 2021 May;
595(7865):85-90.
PMID: 33981037
The ontogeny of the human haematopoietic system during fetal development has previously been characterized mainly through careful microscopic observations. Here we reconstruct a phylogenetic tree of blood development using whole-genome...
9.
Olafsson S, McIntyre R, Coorens T, Butler T, Jung H, Robinson P, et al.
Cell
. 2020 Jul;
182(3):672-684.e11.
PMID: 32697969
Inflammatory bowel disease (IBD) is a chronic inflammatory disease associated with increased risk of gastrointestinal cancers. We whole-genome sequenced 446 colonic crypts from 46 IBD patients and compared these to...
10.
Robinson P, Shall E, Rakhit R
Postgrad Med J
. 2016 Jun;
92(1094):715-720.
PMID: 27281816
Background: Leadership skills directly correlate with the quality of technical performance of cardiopulmonary resuscitation (CPR) and clinical outcomes. Despite an improved focus on non-technical skills in CPR training, the leadership...