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Philip R Streeter

Explore the profile of Philip R Streeter including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 1039
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Recent Articles
1.
Cheng C, Katoch P, Zhong Y, Higgins C, Moredock M, Chang M, et al.
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337350
The basal cell maintains the airway's respiratory epithelium as the putative resident stem cell. Basal cells are known to self-renew and differentiate into airway ciliated and secretory cells. However, it...
2.
Mishra S, Streeter P
Methods Mol Biol . 2022 Dec; 2592:175-184. PMID: 36507993
Innovations in the field of amphiphilic block copolymers have led to the development of a series of attractive polymer-based drug and gene delivery micellar formulations. The amphiphilic block copolymers' low...
3.
Mishra S, Streeter P
Sci Rep . 2022 Nov; 12(1):19127. PMID: 36351917
Type 1 diabetes (T1D) occurs as a consequence of the autoimmune destruction of insulin-producing pancreatic beta (β) cells and commonly presents with insulin deficiency and unregulated glycemic control. Despite improvements...
4.
Parent A, Ashe S, Nair G, Li M, Chavez J, Liu J, et al.
Stem Cell Reports . 2022 Mar; 17(4):979-992. PMID: 35245441
Cell replacement therapy using β cells derived from stem cells is a promising alternative to conventional diabetes treatment options. Although current differentiation methods produce glucose-responsive β cells, they can also...
5.
Saunders K, Jarrell V, Streeter P
Lab Anim (NY) . 2020 Aug; 49(9):236-237. PMID: 32820277
No abstract available.
6.
Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al.
Cell Mol Gastroenterol Hepatol . 2018 Jun; 6(1):79-96. PMID: 29928673
Background & Aims: Continual renewal of the intestinal epithelium is dependent on active- and slow-cycling stem cells that are confined to the crypt base. Tight regulation of these stem cell...
7.
Buenafe A, Streeter P
J Immunol Methods . 2018 May; 459:20-28. PMID: 29758224
We describe here the humanisation of two mouse monoclonal antibodies that bind to surface markers on human pancreatic islet endocrine cells. Monoclonal antibodies produced by the HIC1-2B4 and HIC0-4F9 mouse...
8.
Shi M, Flores B, Li P, Gillings N, McMillan K, Ye J, et al.
Am J Physiol Renal Physiol . 2017 Dec; 314(4):F501-F516. PMID: 29187371
The erythropoietin receptor (EpoR) is widely expressed but its renoprotective action is unexplored. To examine the role of EpoR in vivo in the kidney, we induced acute kidney injury (AKI)...
9.
Cogger K, Sinha A, Sarangi F, McGaugh E, Saunders D, Dorrell C, et al.
Nat Commun . 2017 Aug; 8(1):331. PMID: 28835709
PDX1/NKX6-1 pancreatic progenitors (PPs) give rise to endocrine cells both in vitro and in vivo. This cell population can be successfully differentiated from human pluripotent stem cells (hPSCs) and hold...
10.
Dorrell C, Schug J, Canaday P, Russ H, Tarlow B, Grompe M, et al.
Nat Commun . 2016 Jul; 7:11756. PMID: 27399229
Human pancreatic islets of Langerhans contain five distinct endocrine cell types, each producing a characteristic hormone. The dysfunction or loss of the insulin-producing β cells causes diabetes mellitus, a disease...