Philip Hahnfeldt
Overview
Explore the profile of Philip Hahnfeldt including associated specialties, affiliations and a list of published articles.
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54
Citations
1735
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Recent Articles
21.
Wilkie K, Hahnfeldt P
Cancer Res
. 2013 Mar;
73(12):3534-44.
PMID: 23536560
Cancer in a host induces responses that increase the ability of the microenvironment to sustain the growing mass, for example, angiogenesis, but cancer cells can have varying sensitivities to these...
22.
Hahnfeldt P, Hlatky L, Klement G
Cancer Res
. 2013 Mar;
73(10):2949-54.
PMID: 23492368
Metronomic chemotherapy, the delivery of doses in a low, regular manner so as to avoid toxic side effects, was introduced over 12 years ago in the face of substantial clinical...
23.
Kareva I, Hahnfeldt P
Cancer Res
. 2013 Feb;
73(9):2737-42.
PMID: 23423980
The role of the immune system in tumor elimination has been shown to be increasingly ambiguous, as many tumors not only escape recognition by the adaptive immune response but also...
24.
Beheshti A, Sachs R, Peluso M, Rietman E, Hahnfeldt P, Hlatky L
Radiat Res
. 2013 Jan;
179(2):208-20.
PMID: 23289386
Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data show that from adolescence through middle...
25.
Hillen T, Enderling H, Hahnfeldt P
Bull Math Biol
. 2012 Dec;
75(1):161-84.
PMID: 23196354
Cancer stem cells (CSCs) drive tumor progression, metastases, treatment resistance, and recurrence. Understanding CSC kinetics and interaction with their nonstem counterparts (called tumor cells, TCs) is still sparse, and theoretical...
26.
Hahnfeldt P
Adv Exp Med Biol
. 2012 Nov;
734:19-35.
PMID: 23143973
An increasingly appreciated focus of carcinogenesis research is on mechanisms governing tumor growth after the fact of cancer cell creation. Of particular interest are dynamical interactions between tumor and host...
27.
Enderling H, Hlatky L, Hahnfeldt P
Theor Biol Med Model
. 2012 Jul;
9:31.
PMID: 22838395
Background: The role of the immune system in tumor progression has been a subject for discussion for many decades. Numerous studies suggest that a low immune response might be beneficial,...
28.
Girdhani S, Lamont C, Hahnfeldt P, Abdollahi A, Hlatky L
Radiat Res
. 2012 Jun;
178(1):33-45.
PMID: 22702646
The energy deposition characteristics of proton radiation have attracted considerable attention in light of its implications for carcinogenesis risk in space travel, as well for application to cancer treatment. In...
29.
Enderling H, Hahnfeldt P, Hlatky L, Almog N
Cancer Res
. 2012 Mar;
72(9):2172-5.
PMID: 22414579
For many decades, it has been appreciated that tumor progression is not monotonic, and development of a cancer cell does not equate to inevitable cancer presentation in the clinic. Tumor...
30.
Morton C, Hlatky L, Hahnfeldt P, Enderling H
Theor Biol Med Model
. 2012 Jan;
8:48.
PMID: 22208390
Background: Solid tumors are heterogeneous in composition. Cancer stem cells (CSCs) are believed to drive tumor progression, but the relative frequencies of CSCs versus non-stem cancer cells span wide ranges...