Philip G Williams
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Explore the profile of Philip G Williams including associated specialties, affiliations and a list of published articles.
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66
Citations
2731
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Recent Articles
1.
Raksat A, Atanu M, Mendez S, Zerda R, Sun R, Cheenpracha S, et al.
ACS Omega
. 2024 Apr;
9(16):18516-18525.
PMID: 38680310
The fruit extract of yielded a total of 19 compounds, including two novel spiro-biflavonoid enantiomers ( and ) and a chalcone derivative (). Their structures were determined through spectroscopic analysis....
2.
Back D, ODonnell T, Axt K, Gurr J, Vanegas J, Williams P, et al.
ACS Chem Biol
. 2023 Jul;
18(8):1797-1807.
PMID: 37487226
Cyanobacteria are tremendous producers of biologically active natural products, including the potent anti-inflammatory compound tolypodiol. However, linking biosynthetic gene clusters with compound production in cyanobacteria has lagged behind that in...
3.
Dai J, Philbin C, Wakano C, Yoshida W, Williams P
Mar Drugs
. 2023 Feb;
21(2).
PMID: 36827142
Six new nostocyclophanes and four known compounds have been isolated from (Nostocaceae) cyanobacterial strain UTEX B1932. The new compounds, nostocyclophanes E-J (-), were characterized by NMR and MS techniques. The...
4.
Liu F, ODonnell T, Park E, Kovacs S, Nakamura K, Dave A, et al.
J Nat Prod
. 2023 Feb;
86(2):276-289.
PMID: 36746775
Sixteen new quinoline alkaloids (-, , , , -, , and ) and 10 known analogs (, , , , -, and -), along with three known cyclopeptide alkaloids (-),...
5.
Liu F, Mallick S, ODonnell T, Rouzimaimaiti R, Luo Y, Sun R, et al.
Molecules
. 2022 May;
27(10).
PMID: 35630746
Seven new coumarinolignans, walthindicins A-F (, , -, ), along with five known analogs (, -), were isolated from the roots of . The structures of the new compounds are...
6.
Lipopolysaccharide from the Cyanobacterium sp. Induces Neutrophil Infiltration and Lung Inflammation
Swartzendruber J, Monroy Del Toro R, Incrocci R, Seangmany N, Gurr J, Mayer A, et al.
Toxins (Basel)
. 2022 Apr;
14(4).
PMID: 35448876
Glucocorticoid-resistant asthma, which predominates with neutrophils instead of eosinophils, is an increasing health concern. One potential source for the induction of neutrophil-predominant asthma is aerosolized lipopolysaccharide (LPS). Cyanobacteria have recently...
7.
ODonnell T, Luo Y, Yoshida W, Suzuki S, Sun R, Williams P
J Nat Prod
. 2022 Feb;
85(2):415-425.
PMID: 35142496
As part of a study examining polar metabolites produced by cyanobacterial strains, we examined media extracts of a sp. (strain R-3-1) and a sp. (strain U-3-3). The cell mass of...
8.
Dow A, Sule P, ODonnell T, Burger A, Mattila J, Antonio B, et al.
PLoS Pathog
. 2021 May;
17(5):e1009570.
PMID: 33989345
Mycobacterium tuberculosis (Mtb) has complex and dynamic interactions with the human host, and subpopulations of Mtb that emerge during infection can influence disease outcomes. This study implicates zinc ion (Zn2+)...
9.
Li N, Han Z, ODonnell T, Kurasaki R, Kajihara L, Williams P, et al.
Appl Microbiol Biotechnol
. 2020 Jul;
104(16):6977-6989.
PMID: 32601736
This study aimed to develop a bioprocess using plant oil as the carbon source for lipid-assimilating yeast to produce high-value astaxanthin. Using high-oleic safflower oil as a model, efficient cell...
10.
Gurr J, ODonnell T, Luo Y, Yoshida W, Hall M, Mayer A, et al.
J Nat Prod
. 2020 Apr;
83(5):1691-1695.
PMID: 32282204
Chemical investigation of cyanobacterial strain HT-58-2, which most closely aligns with the genus , has led to the isolation of two compounds related to tolypodiol. The structures and absolute configuration...