Philip Cayting
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Explore the profile of Philip Cayting including associated specialties, affiliations and a list of published articles.
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12
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3782
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Recent Articles
1.
Cheng Y, Ma Z, Kim B, Wu W, Cayting P, Boyle A, et al.
Nature
. 2014 Nov;
515(7527):371-375.
PMID: 25409826
To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors (TFs) in human-mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines....
2.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, et al.
Nature
. 2014 Nov;
515(7527):355-64.
PMID: 25409824
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To...
3.
Boyle A, Araya C, Brdlik C, Cayting P, Cheng C, Cheng Y, et al.
Nature
. 2014 Aug;
512(7515):453-6.
PMID: 25164757
Despite the large evolutionary distances between metazoan species, they can show remarkable commonalities in their biology, and this has helped to establish fly and worm as model organisms for human...
4.
Landt S, Marinov G, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, et al.
Genome Res
. 2012 Sep;
22(9):1813-31.
PMID: 22955991
Chromatin immunoprecipitation (ChIP) followed by high-throughput DNA sequencing (ChIP-seq) has become a valuable and widely used approach for mapping the genomic location of transcription-factor binding and histone modifications in living...
5.
Gerstein M, Kundaje A, Hariharan M, Landt S, Yan K, Cheng C, et al.
Nature
. 2012 Sep;
489(7414):91-100.
PMID: 22955619
Transcription factors bind in a combinatorial fashion to specify the on-and-off states of genes; the ensemble of these binding events forms a regulatory network, constituting the wiring diagram for a...
6.
Stamatoyannopoulos J, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert D, et al.
Genome Biol
. 2012 Aug;
13(8):418.
PMID: 22889292
To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the same experimental pipelines...
7.
Khurana E, Lam H, Cheng C, Carriero N, Cayting P, Gerstein M
Nucleic Acids Res
. 2010 Jul;
38(20):6997-7007.
PMID: 20615899
Duplicated pseudogenes in the human genome are disabled copies of functioning parent genes. They result from block duplication events occurring throughout evolutionary history. Relatively recent duplications (with sequence similarity≥90% and...
8.
Korbel J, Abyzov A, Mu X, Carriero N, Cayting P, Zhang Z, et al.
Genome Biol
. 2009 Feb;
10(2):R23.
PMID: 19236709
Personal-genomics endeavors, such as the 1000 Genomes project, are generating maps of genomic structural variants by analyzing ends of massively sequenced genome fragments. To process these we developed Paired-End Mapper...
9.
Balasubramanian S, Zheng D, Liu Y, Fang G, Frankish A, Carriero N, et al.
Genome Biol
. 2009 Jan;
10(1):R2.
PMID: 19123937
Background: The availability of genome sequences of numerous organisms allows comparative study of pseudogenes in syntenic regions. Conservation of pseudogenes suggests that they might have a functional role in some...
10.
Lam H, Khurana E, Fang G, Cayting P, Carriero N, Cheung K, et al.
Nucleic Acids Res
. 2008 Oct;
37(Database issue):D738-43.
PMID: 18957444
Pseudofam (http://pseudofam.pseudogene.org) is a database of pseudogene families based on the protein families from the Pfam database. It provides resources for analyzing the family structure of pseudogenes including query tools,...