Petra Paclikova
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Explore the profile of Petra Paclikova including associated specialties, affiliations and a list of published articles.
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10
Citations
118
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Recent Articles
1.
Ntourmas S, Sachs M, Paclikova P, Bruckner M, Bryja V, Behrens J, et al.
Elife
. 2024 Dec;
13.
PMID: 39652469
Activation of the Wnt/β-catenin pathway crucially depends on the polymerization of dishevelled 2 (DVL2) into biomolecular condensates. However, given the low affinity of known DVL2 self-interaction sites and its low...
2.
Paclikova P, Harnos J
Sci Rep
. 2024 Sep;
14(1):21591.
PMID: 39284917
This study introduces a novel cost-effective technique for cloning of linear DNA plasmid inserts, aiming to address the associated expenses linked with popular in vitro DNA assembly methods. Specifically, we...
3.
Falginella F, Kravec M, Drabinova M, Paclikova P, Bryja V, Vacha R
Biochim Biophys Acta Biomembr
. 2022 Jun;
1864(10):183983.
PMID: 35750206
Over the past decades an extensive effort has been made to provide a more comprehensive understanding of Wnt signaling, yet many regulatory and structural aspects remain elusive. Among these, the...
4.
Paclikova P, Radaszkiewicz T, Potesil D, Harnos J, Zdrahal Z, Bryja V
Cell Signal
. 2021 Jun;
85:110058.
PMID: 34082011
Dishevelled (DVL) proteins are key mediators of most Wnt pathways. In all vertebrates, three DVL paralogs are present (DVL1, DVL2 and DVL3) but it is poorly defined to what extent...
5.
Bernatik O, Paclikova P, Kotrbova A, Bryja V, cajanek L
Front Cell Dev Biol
. 2021 Mar;
9:623753.
PMID: 33718363
Primary cilia act as crucial regulators of embryo development and tissue homeostasis. They are instrumental for modulation of several signaling pathways, including Hedgehog, WNT, and TGF-β. However, gaps exist in...
6.
Jurasek M, Kumar J, Paclikova P, Kumari A, Tripsianes K, Bryja V, et al.
Sci Rep
. 2021 Jan;
11(1):1484.
PMID: 33452274
The PDZ domain of Dishevelled 3 protein belongs to a highly abundant protein recognition motif which typically binds short C-terminal peptides. The affinity of the PDZ towards the peptides could...
7.
Bernatik O, Paclikova P, Sri Ganji R, Bryja V
Cells
. 2020 May;
9(5).
PMID: 32392721
Wnt and BMP signaling pathways are two key molecular machineries regulating development and homeostasis. The efficient coordination of Wnt and BMP is essential in many developmental processes such as establishment...
8.
Hanakova K, Bernatik O, Kravec M, Micka M, Kumar J, Harnos J, et al.
Cell Commun Signal
. 2019 Dec;
17(1):170.
PMID: 31870452
Background: Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and...
9.
Lee Y, Kim N, Cho E, Yang J, Cha Y, Kang H, et al.
Nat Commun
. 2018 Jun;
9(1):2301.
PMID: 29895829
Phosphorylation-dependent YAP translocation is a well-known intracellular mechanism of the Hippo pathway; however, the molecular effectors governing YAP cytoplasmic translocation remains undefined. Recent findings indicate that oncogenic YAP paradoxically suppresses...
10.
Paclikova P, Bernatik O, Radaszkiewicz T, Bryja V
Mol Cell Biol
. 2017 Jul;
37(18).
PMID: 28674183
Dishevelled (DVL) proteins are key mediators of the Wnt/β-catenin signaling pathway. All DVL proteins contain three conserved domains: DIX, PDZ, and DEP. There is a consensus in the field that...