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Tomasz Witold Radaszkiewicz

Explore the profile of Tomasz Witold Radaszkiewicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 65
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Recent Articles
1.
Sladecek S, Radaszkiewicz K, Bohmova M, Gybel T, Radaszkiewicz T, Pachernik J
PLoS One . 2022 Oct; 17(10):e0275860. PMID: 36227898
Dual specificity phosphatase 7 (DUSP7) is a protein belonging to a broad group of phosphatases that can dephosphorylate phosphoserine/phosphothreonine as well as phosphotyrosine residues within the same substrate. DUSP7 has...
2.
Paclikova P, Radaszkiewicz T, Potesil D, Harnos J, Zdrahal Z, Bryja V
Cell Signal . 2021 Jun; 85:110058. PMID: 34082011
Dishevelled (DVL) proteins are key mediators of most Wnt pathways. In all vertebrates, three DVL paralogs are present (DVL1, DVL2 and DVL3) but it is poorly defined to what extent...
3.
Radaszkiewicz K, Beckerova D, Woloszczukova L, Radaszkiewicz T, Lesakova P, Vondalova Blanarova O, et al.
Sci Rep . 2020 Sep; 10(1):15922. PMID: 32985604
12-O-Tetradecanoylphorbol-13-acetate (TPA) is the most widely used diacylglycerol (DAG) mimetic agent and inducer of protein kinase C (PKC)-mediated cellular response in biomedical studies. TPA has been proposed as a pluripotent...
4.
Harnos J, Canizal M, Jurasek M, Kumar J, Holler C, Schambony A, et al.
Nat Commun . 2019 Apr; 10(1):1804. PMID: 31000703
Dishevelled (DVL) is the key component of the Wnt signaling pathway. Currently, DVL conformational dynamics under native conditions is unknown. To overcome this limitation, we develop the Fluorescein Arsenical Hairpin...
5.
Paclikova P, Bernatik O, Radaszkiewicz T, Bryja V
Mol Cell Biol . 2017 Jul; 37(18). PMID: 28674183
Dishevelled (DVL) proteins are key mediators of the Wnt/β-catenin signaling pathway. All DVL proteins contain three conserved domains: DIX, PDZ, and DEP. There is a consensus in the field that...