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Petra I zur Lage

Explore the profile of Petra I zur Lage including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Moore D, Onoufriadis A, Shoemark A, Simpson M, zur Lage P, De Castro S, et al.
Am J Hum Genet . 2013 Jul; 93(2):346-56. PMID: 23891471
Primary ciliary dyskinesia (PCD) is a ciliopathy characterized by airway disease, infertility, and laterality defects, often caused by dual loss of the inner dynein arms (IDAs) and outer dynein arms...
2.
Cipressa F, Romano S, Centonze S, zur Lage P, Verni F, Dimitri P, et al.
Genetics . 2013 Jul; 195(1):147-58. PMID: 23821599
Drosophila telomeres are elongated by the transposition of telomere-specific retrotransposons rather than telomerase activity. Proximal to the terminal transposon array, Drosophila chromosomes contain several kilobases of a complex satellite DNA...
3.
Newton F, zur Lage P, Karak S, Moore D, Gopfert M, Jarman A
Dev Cell . 2012 Jun; 22(6):1221-33. PMID: 22698283
Cilia have evolved hugely diverse structures and functions to participate in a wide variety of developmental and physiological processes. Ciliary specialization requires differences in gene expression, but few transcription factors...
4.
zur Lage P, Simpson T, Jarman A
Fly (Austin) . 2011 May; 5(4):322-6. PMID: 21558799
Much of developmental biology is concerned with the processes by which cells become committed to particular fates in a regulated fashion, whereas cell biology addresses, among other things, the variety...
5.
Cachero S, Simpson T, zur Lage P, Ma L, Newton F, Holohan E, et al.
PLoS Biol . 2011 Feb; 9(1):e1000568. PMID: 21283833
In neurogenesis, neural cell fate specification is generally triggered by proneural transcription factors. Whilst the role of proneural factors in fate specification is well studied, the link between neural specification...
6.
zur Lage P, Jarman A
BMC Dev Biol . 2010 Mar; 10:34. PMID: 20346138
Background: bHLH transcription factors play many roles in neural development. cousin of atonal (cato) encodes one such factor that is expressed widely in the developing sensory nervous system of Drosophila....
7.
Holohan E, zur Lage P, Jarman A
BMC Dev Biol . 2006 Nov; 6:53. PMID: 17094800
Background: The regulation of proneural gene expression is an important aspect of neurogenesis. In the study of the Drosophila proneural genes, scute and atonal, several themes have emerged that contribute...
8.
zur Lage P, Powell L, Prentice D, McLaughlin P, Jarman A
Dev Cell . 2004 Nov; 7(5):687-96. PMID: 15525530
In Drosophila, commitment of a cell to a sense organ precursor (SOP) fate requires bHLH proneural transcription factor upregulation, a process that depends in most cases on the interplay of...
9.
Powell L, zur Lage P, Prentice D, Senthinathan B, Jarman A
Mol Cell Biol . 2004 Oct; 24(21):9517-26. PMID: 15485919
For a particular functional family of basic helix-loop-helix (bHLH) transcription factors, there is ample evidence that different factors regulate different target genes but little idea of how these different target...
10.
zur Lage P, Prentice D, Holohan E, Jarman A
Development . 2003 Aug; 130(19):4683-93. PMID: 12925594
Proneural genes encode basic-helix-loop-helix (bHLH) transcription factors required for neural precursor specification. Recently amos was identified as a new candidate Drosophila proneural gene related to atonal. Having isolated the first...