Petra Breiden
Overview
Explore the profile of Petra Breiden including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
508
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0
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Recent Articles
1.
Hausrat T, Janiesch P, Breiden P, Lutz D, Hoffmeister-Ullerich S, Hermans-Borgmeyer I, et al.
Nat Commun
. 2022 Jul;
13(1):4192.
PMID: 35858909
Dissociation of hyper-phosphorylated Tau from neuronal microtubules and its pathological aggregates, are hallmarks in the etiology of tauopathies. The Tau-microtubule interface is subject to polyglutamylation, a reversible posttranslational modification, increasing...
2.
Muhia M, Yuanxiang P, Sedlacik J, Schwarz J, Heisler F, Gromova K, et al.
Commun Biol
. 2022 Jun;
5(1):589.
PMID: 35705737
Muskelin (Mkln1) is implicated in neuronal function, regulating plasma membrane receptor trafficking. However, its influence on intrinsic brain activity and corresponding behavioral processes remains unclear. Here we show that murine...
3.
Lopes A, Hausrat T, Heisler F, Gromova K, Lombino F, Fischer T, et al.
PLoS Biol
. 2020 Sep;
18(8):e3000820.
PMID: 32866173
Mutations in the gene encoding the microtubule-severing protein spastin (spastic paraplegia 4 [SPG4]) cause hereditary spastic paraplegia (HSP), associated with neurodegeneration, spasticity, and motor impairment. Complicated forms (complicated HSP [cHSP])...
4.
Hausrat T, Radwitz J, Lombino F, Breiden P, Kneussel M
Dev Neurobiol
. 2020 Apr;
81(3):333-350.
PMID: 32293117
Alpha- and beta-tubulin dimers polymerize into protofilaments that associate laterally to constitute a hollow tube, the microtubule. A dynamic network of interlinking filaments forms the microtubule cytoskeleton, which maintains the...
5.
Hausrat T, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, et al.
Nat Commun
. 2015 Apr;
6:6872.
PMID: 25891999
Neurotransmitter receptor density is a major variable in regulating synaptic strength. Receptors rapidly exchange between synapses and intracellular storage pools through endocytic recycling. In addition, lateral diffusion and confinement exchanges...
6.
Rathgeber L, Gromova K, Schaefer I, Breiden P, Lohr C, Kneussel M
Eur J Cell Biol
. 2015 Feb;
94(3-4):173-8.
PMID: 25701174
The kinesin KIF5 transports neuronal cargoes into axons and dendrites. Isolated KIF5 motor domains preferentially move into axons, however KIF5 binding to GRIP1 or gephyrin drives the motor into dendrites,...
7.
Lutterotti A, Yousef S, Sputtek A, Sturner K, Stellmann J, Breiden P, et al.
Sci Transl Med
. 2013 Jun;
5(188):188ra75.
PMID: 23740901
Multiple sclerosis (MS) is a devastating inflammatory disease of the brain and spinal cord that is thought to result from an autoimmune attack directed against antigens in the central nervous...
8.
Tillack K, Breiden P, Martin R, Sospedra M
J Immunol
. 2012 Feb;
188(7):3150-9.
PMID: 22351936
Polymorphonuclear neutrophils constitute the first line of defense against infections. Among their strategies to eliminate pathogens they release neutrophil extracellular traps (NETs), being chromatin fibers decorated with antimicrobial proteins. NETs...
9.
Jelcic I, Hsu K, Kakalacheva K, Breiden P, Dupont B, Uhrberg M, et al.
Mult Scler
. 2011 Dec;
18(7):951-8.
PMID: 22185807
Objective: The objective of this study was to analyze whether inhibitory and activating killer cell immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I alleles defined by their KIR...
10.
Aly L, Yousef S, Schippling S, Jelcic I, Breiden P, Matschke J, et al.
Brain
. 2011 Sep;
134(Pt 9):2687-702.
PMID: 21908874
Progressive multi-focal leucoencephalopathy and progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome are caused by infection of the central nervous system with the JC polyoma virus. Both are complications of monoclonal antibody...