Petr Busek
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Explore the profile of Petr Busek including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
456
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Recent Articles
1.
Pfeiferova L, Spanko M, Sachova J, Hradilova M, Pienta K, Valach J, et al.
Histochem Cell Biol
. 2025 Mar;
163(1):38.
PMID: 40063181
Fibroblasts, the most abundant cell type in the human body, play crucial roles in biological processes such as inflammation and cancer progression. They originate from the mesoderm or neural-crest-derived ectomesenchyme....
2.
Cermakova K, Simkova A, Wichterle F, Krystufek R, Stanurova J, Vanickova Z, et al.
Eur J Med Chem
. 2024 Oct;
280:116948.
PMID: 39437576
Fibroblast activation protein (FAP) has been extensively studied as a cancer biomarker for decades. Recently, small-molecule FAP inhibitors have been widely adopted as a targeting moiety of experimental theranostic radiotracers....
3.
Skarkova A, Pelantova M, Tolde O, Legatova A, Mateu R, Busek P, et al.
Brain Pathol
. 2024 Aug;
35(1):e13294.
PMID: 39097525
Glioblastomas are aggressive brain tumors for which effective therapy is still lacking, resulting in dismal survival rates. These tumors display significant phenotypic plasticity, harboring diverse cell populations ranging from tumor...
4.
Fibrillar extracellular matrix produced by pericyte-like cells facilitates glioma cell dissemination
Vymola P, Garcia-Borja E, cervenka J, Balaziova E, Vymolova B, Veprkova J, et al.
Brain Pathol
. 2024 May;
34(6):e13265.
PMID: 38705944
Gliomagenesis induces profound changes in the composition of the extracellular matrix (ECM) of the brain. In this study, we identified a cellular population responsible for the increased deposition of collagen...
5.
Konecna D, Vymola P, Ternerova N, Vymolova B, Garcia-Borja E, Mateu R, et al.
J Neurosurg
. 2024 Mar;
141(3):602-613.
PMID: 38552239
Objective: The highly infiltrative growth of glioblastoma (GBM) makes distinction between the tumor and normal brain tissue challenging. Therefore, fluorescence-guided surgery is often used to improve visual identification of radiological...
6.
Garcia-Borja E, Siegl F, Mateu R, Slaby O, Sedo A, Busek P, et al.
Biomark Res
. 2024 Feb;
12(1):15.
PMID: 38303021
Small noncoding RNAs play an important role in various disease states, including cancer. PIWI proteins, a subfamily of Argonaute proteins, and PIWI-interacting RNAs (piRNAs) were originally described as germline-specific molecules...
7.
Kejik Z, Koubkova N, Krcova L, Sykora D, Abramenko N, Vesela K, et al.
Bioorg Chem
. 2023 Sep;
141:106816.
PMID: 37716274
Pentamethinium indolium salts are promising fluorescence probes and anticancer agents with high mitochondrial selectivity. We synthesized two indolium pentamethinium salts: a cyclic form with quinoxaline directly incorporated in the pentamethinium...
8.
Zubal M, Vymolova B, Matrasova I, Vymola P, Veprkova J, Syrucek M, et al.
Pathology
. 2023 Jul;
55(6):806-817.
PMID: 37419841
Brain metastases are a very common and serious complication of oncological diseases. Despite the vast progress in multimodality treatment, brain metastases significantly decrease the quality of life and prognosis of...
9.
Talianova V, Kejik Z, Kaplanek R, Vesela K, Abramenko N, Lacina L, et al.
Pharmaceutics
. 2022 Aug;
14(8).
PMID: 36015338
IL-6 signaling is involved in the pathogenesis of a number of serious diseases, including chronic inflammation and cancer. Targeting of IL-6 receptor (IL-6R) by small molecules is therefore an intensively...
10.
Busek P, Duke-Cohan J, Sedo A
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565202
Dipeptidyl peptidase IV (DPP-IV, CD26) is frequently dysregulated in cancer and plays an important role in regulating multiple bioactive peptides with the potential to influence cancer progression and the recruitment...