Peter W Nathanielsz
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Explore the profile of Peter W Nathanielsz including associated specialties, affiliations and a list of published articles.
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244
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4775
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Recent Articles
1.
Huber H, Ainsworth H, Quillen E, Salmon A, Ross C, Azhar A, et al.
Geroscience
. 2024 Nov;
47(1):135-151.
PMID: 39585646
There is a critical need to generate age- and sex-specific survival curves to characterize chronological aging consistently across nonhuman primates (NHP) used in biomedical research. Sex-specific Kaplan-Meier survival curves were...
2.
Cox L, Puppala S, Chan J, Riojas A, Lange K, Birnbaum S, et al.
J Dev Orig Health Dis
. 2024 Nov;
15:e27.
PMID: 39506415
Previous studies in rodents suggest that mismatch between fetal and postnatal nutrition predisposes individuals to metabolic diseases. We hypothesized that in nonhuman primates (NHP), fetal programming of maternal undernutrition (MUN)...
3.
Adekunbi D, Huber H, Benavides G, Tian R, Li C, Nathanielsz P, et al.
bioRxiv
. 2024 Oct;
PMID: 39386547
Mitochondria play a crucial role in brain aging due to their involvement in bioenergetics, neuroinflammation and brain steroid synthesis. Mitochondrial dysfunction is linked to age-related neurodegenerative diseases, including Alzheimer's disease...
4.
Meakin A, Nathanielsz P, Li C, Huber H, Clifton V, Wiese M, et al.
Obesity (Silver Spring)
. 2024 Aug;
32(10):1910-1922.
PMID: 39210592
Objective: Maternal obesity (MO) increases the risk of later-life liver disease in offspring, especially in males. This may be due to impaired cytochrome P450 (CYP) enzyme activity driven by an...
5.
Huber H, Ainsworth H, Quillen E, Salmon A, Ross C, Azhar A, et al.
bioRxiv
. 2024 Aug;
PMID: 39131309
There is a critical need to generate age- and sex-specific survival curves to characterize chronological aging consistently across nonhuman primates (NHP) used in biomedical research. Sex-specific Kaplan-Meier survival curves were...
6.
Grilo L, Zimmerman K, Puppala S, Chan J, Huber H, Li G, et al.
Adv Sci (Weinh)
. 2024 Aug;
11(38):e2309211.
PMID: 39119859
Age is a prominent risk factor for cardiometabolic disease, often leading to heart structural and functional changes. However, precise molecular mechanisms underlying cardiac remodeling and dysfunction exclusively resulting from physiological...
7.
Bertossa M, Darby J, Holman S, Meakin A, Li C, Huber H, et al.
J Physiol
. 2024 Aug;
602(17):4251-4269.
PMID: 39087821
The consumption of high fat-high energy diets (HF-HEDs) continues to rise worldwide and parallels the rise in maternal obesity (MO) that predisposes offspring to cardiometabolic disorders. Although the underlying mechanisms...
8.
Adekunbi D, Yang B, Huber H, Riojas A, Moody A, Li C, et al.
bioRxiv
. 2024 May;
PMID: 38746316
We previously demonstrated in baboons that maternal undernutrition (MUN), achieved by 70 % of control nutrition, impairs fetal liver function, but long-term changes associated with aging in this model remain...
9.
Adekunbi D, Huber H, Li C, Nathanielsz P, Cox L, Salmon A
Geroscience
. 2024 Apr;
46(5):4443-4459.
PMID: 38607532
Biological resilience, broadly defined as the ability to recover from an acute challenge and return to homeostasis, is of growing importance to the biology of aging. At the cellular level,...
10.
Ibanez C, Correa F, Lira-Leon G, Reyes-Castro L, Roldan F, Silva-Palacios A, et al.
Arch Med Res
. 2024 Mar;
55(3):102983.
PMID: 38492326
Maternal obesity predisposes offspring (F1) to cardiovascular disease. To evaluate basal heart function and ischemia-reperfusion (IR) responses in F1 males and females of obese mothers, female Wistar rats (F0) were...