Peter Vandenabeele
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Explore the profile of Peter Vandenabeele including associated specialties, affiliations and a list of published articles.
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357
Citations
33903
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Recent Articles
11.
Cappe B, Vadi M, Sack E, Wacheul L, Verstraeten B, Dufour S, et al.
J Extracell Vesicles
. 2023 Oct;
12(10):e12365.
PMID: 37807017
Formation of extracellular vesicles (EVs) has emerged as a novel paradigm in cell-to-cell communication in health and disease. EVs are notably produced during cell death but it had remained unclear...
12.
Van San E, Debruyne A, Veeckmans G, Tyurina Y, Tyurin V, Zheng H, et al.
Cell Death Differ
. 2023 Aug;
30(9):2092-2103.
PMID: 37542104
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by central nervous (CNS) demyelination resulting in axonal injury and neurological deficits. Essentially, MS is driven by an auto-amplifying mechanism of...
13.
Sprooten J, Laureano R, Vanmeerbeek I, Govaerts J, Naulaerts S, Borras D, et al.
Oncoimmunology
. 2023 Jun;
12(1):2219591.
PMID: 37284695
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell death that activates, rather than suppresses, innate and adaptive immune responses. Such responses culminate into T cell-driven...
14.
Vitale I, Pietrocola F, Guilbaud E, Aaronson S, Abrams J, Adam D, et al.
Cell Death Differ
. 2023 Apr;
30(5):1097-1154.
PMID: 37100955
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have...
15.
Fernandez-Acosta R, Hassannia B, Caroen J, Wiernicki B, Alvarez-Alminaque D, Verstraeten B, et al.
Cells
. 2023 Mar;
12(5).
PMID: 36899871
Ferroptosis is an iron-dependent cell death-driven by excessive peroxidation of polyunsaturated fatty acids (PUFAs) of membranes. A growing body of evidence suggests the induction of ferroptosis as a cutting-edge strategy...
16.
M C, Pippia G, Tanghe I, Martin-Garcia B, Rousaki A, Vandenabeele P, et al.
J Phys Chem Lett
. 2023 Mar;
14(10):2620-2626.
PMID: 36888728
Transition metal dichalcogenides (TMDs) are nanostructured semiconductors with prospects in optoelectronics and photocatalysis. Several bottom-up procedures to synthesize such materials have been developed yielding colloidal transition metal dichalcogenides (c-TMDs). Where...
17.
Solier S, Mondini M, Meziani L, Jacquel A, Lacout C, Vanden Berghe T, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835566
Circulating monocytes are recruited in damaged tissues to generate macrophages that modulate disease progression. Colony-stimulating factor-1 (CSF-1) promotes the generation of monocyte-derived macrophages, which involves caspase activation. Here, we demonstrate...
18.
Van Eeckhoutte H, Donovan C, Kim R, Conlon T, Ansari M, Khan H, et al.
Eur Respir J
. 2022 Dec;
61(4).
PMID: 36549711
Background: Receptor-interacting protein kinase 1 (RIPK1) is a key mediator of regulated cell death (including apoptosis and necroptosis) and inflammation, both drivers of COPD pathogenesis. We aimed to define the...
19.
Vandenabeele P, Bultynck G, Savvides S
Nat Rev Mol Cell Biol
. 2022 Dec;
24(5):312-333.
PMID: 36543934
Regulated cell death (RCD) relies on activation and recruitment of pore-forming proteins (PFPs) that function as executioners of specific cell death pathways: apoptosis regulator BAX (BAX), BCL-2 homologous antagonist/killer (BAK)...
20.
Nemegeer J, Lemeire K, Vandenabeele P, Maelfait J
J Vis Exp
. 2022 Nov;
(188).
PMID: 36342164
The kinase Receptor-interacting serine/threonine protein kinase 3 (RIPK3) and its substrate mixed lineage kinase domain-like (MLKL) are critical regulators of necroptosis, an inflammatory form of cell death with important antiviral...