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Peter R Hoffmann

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Articles 75
Citations 2766
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Recent Articles
1.
Cai Z, Zhang Y, He L, Cui M, Zhang W, E L, et al.
J Agric Food Chem . 2025 Mar; PMID: 40071728
Chronic exposure to arsenic (As), a ubiquitous contaminant, poses deleterious health risks to humans, including cardiovascular disease. Recent studies have implicated ferroptosis, in which the essential micronutrient selenium (Se) plays...
2.
Bothner B, Lusetti S, Seville R, Baker J, Barnes B, Hoffmann P, et al.
Adv Physiol Educ . 2025 Feb; 49(2):374-385. PMID: 39946679
Since 2001, the National Institutes of Health (NIH) have funded the Institutional Development Award (IDeA) Network of Biomedical Research Excellence (INBRE) to expand biomedical research capacity among states in which...
3.
Marcantonio E, Burger A, Chang K, Hoffmann F, Fu Y, Khadka V, et al.
Infect Immun . 2025 Feb; 93(3):e0057824. PMID: 39903447
Tuberculosis (TB) is notoriously difficult to treat, likely due to the complex host-pathogen interactions driven by pathogen heterogeneity. An understudied area of TB pathogenesis is host responses to bacteria (Mtb)...
4.
Yang H, Wang Z, Li L, Wang X, Wei X, Gou S, et al.
J Nanobiotechnology . 2024 Oct; 22(1):613. PMID: 39385176
Impaired intestinal homeostasis is a major pathological feature of inflammatory bowel diseases (IBD). Mannose and selenium (Se) both demonstrate potential anti-inflammatory and anti-oxidative properties. However, most lectin receptors bind free...
5.
Green K, Ma C, Hoffmann F, Hoffmann P, Green W
Virology . 2024 Sep; 600:110247. PMID: 39307098
We have shown the induction of CD11bLy6C monocytic myeloid-derived suppressor cells (M-MDSCs) during infection of B6 mice by LP-BM5 immunodeficiency-inducing retrovirus. We published that the molecular mechanisms of these M-MDSCs...
6.
Nunes L, Ma C, Hoffmann F, Shay A, Pitts M, Hoffmann P
J Biol Chem . 2024 Apr; 300(5):107259. PMID: 38582453
Selenoprotein I (SELENOI) catalyzes the final reaction of the CDP-ethanolamine branch of the Kennedy pathway, generating the phospholipids phosphatidylethanolamine (PE) and plasmenyl-PE. Plasmenyl-PE is a key component of myelin and...
7.
Brampton C, Pomozi V, Le Corre Y, Zoll J, Kauffenstein G, Ma C, et al.
J Invest Dermatol . 2024 Feb; 144(8):1772-1783.e3. PMID: 38367909
Physiological calcification of soft tissues is a common occurrence in aging and various acquired and inherited disorders. ABCC6 sequence variations cause the calcification phenotype of pseudoxanthoma elasticum (PXE) as well...
8.
Ma C, Hoffmann F, Shay A, Koo I, Green K, Green W, et al.
J Leukoc Biol . 2024 Jan; 116(1):6-17. PMID: 38289835
The mechanisms driving metabolic reprogramming during B cell activation are unclear, particularly roles for enzymatic pathways involved in lipid remodeling. We found that murine B cell activation with lipopolysaccharide (LPS)...
9.
Nunes L, Cain A, Comyns C, Hoffmann P, Krahn N
Antioxidants (Basel) . 2023 Nov; 12(11). PMID: 38001759
Selenocysteine (Sec), the 21st amino acid, is structurally similar to cysteine but with a sulfur to selenium replacement. This single change retains many of the chemical properties of cysteine but...
10.
Morosky P, Comyns C, Nunes L, Chung C, Hoffmann P, Soll D, et al.
Front Mol Biosci . 2023 Feb; 10:1096261. PMID: 36762212
Post-translational modifications (PTMs) can occur on almost all amino acids in eukaryotes as a key mechanism for regulating protein function. The ability to study the role of these modifications in...