Peter L Wang
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Explore the profile of Peter L Wang including associated specialties, affiliations and a list of published articles.
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40
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3043
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Recent Articles
1.
Dehghannasiri R, Kokot M, Starr A, Maziarz J, Gordon T, Tan S, et al.
bioRxiv
. 2025 Jan;
PMID: 39763839
Typical high-throughput single-cell RNA-sequencing (scRNA-seq) analyses are primarily conducted by (pseudo)alignment, through the lens of annotated gene models, and aimed at detecting differential gene expression. This misses diversity generated by...
2.
Shiau C, Cao J, Gong D, Gregory M, Caldwell N, Yin X, et al.
Nat Genet
. 2024 Sep;
56(11):2466-2478.
PMID: 39227743
In combination with cell-intrinsic properties, interactions in the tumor microenvironment modulate therapeutic response. We leveraged single-cell spatial transcriptomics to dissect the remodeling of multicellular neighborhoods and cell-cell interactions in human...
3.
Chaung K, Baharav T, Henderson G, Zheludev I, Wang P, Salzman J
Cell
. 2023 Dec;
186(25):5440-5456.e26.
PMID: 38065078
Today's genomics workflows typically require alignment to a reference sequence, which limits discovery. We introduce a unifying paradigm, SPLASH (Statistically Primary aLignment Agnostic Sequence Homing), which directly analyzes raw sequencing...
4.
Abante J, Wang P, Salzman J
Genome Biol
. 2023 Oct;
24(1):240.
PMID: 37864197
Diversity-generating and mobile genetic elements are key to microbial and viral evolution and can result in evolutionary leaps. State-of-the-art algorithms to detect these elements have limitations. Here, we introduce DIVE,...
5.
Chaung K, Baharav T, Henderson G, Zheludev I, Wang P, Salzman J
bioRxiv
. 2023 Jul;
PMID: 37503014
The authors have withdrawn this manuscript due to a duplicate posting of manuscript number BIORXIV/2022/497555. Therefore, the authors do not wish this work to be cited as reference for the...
6.
Shiau C, Cao J, Gregory M, Gong D, Yin X, Cho J, et al.
bioRxiv
. 2023 Jul;
PMID: 37425692
In combination with cell intrinsic properties, interactions in the tumor microenvironment modulate therapeutic response. We leveraged high-plex single-cell spatial transcriptomics to dissect the remodeling of multicellular neighborhoods and cell-cell interactions...
7.
Wang P, Djerboua M, Flemming J
Hepatol Commun
. 2023 Jun;
7(7).
PMID: 37378630
Background: Although patients with cirrhosis are at increased risk of death, the exact causes of death have not been reported in the contemporary era. This study aimed to describe cause-specific...
8.
Hu X, Du L, Liu S, Lan Z, Zang K, Feng J, et al.
J Clin Invest
. 2023 Jan;
133(5.
PMID: 36701202
Microglia, resident macrophages of the CNS, are essential to brain development, homeostasis, and disease. Microglial activation and proliferation are hallmarks of many CNS diseases, including neuropathic pain. However, molecular mechanisms...
9.
Dingwall C, Strickland A, Yum S, Yim A, Zhu J, Wang P, et al.
J Clin Invest
. 2022 Oct;
132(23.
PMID: 36287209
Axon loss contributes to many common neurodegenerative disorders. In healthy axons, the axon survival factor NMNAT2 inhibits SARM1, the central executioner of programmed axon degeneration. We identified 2 rare NMNAT2...
10.