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Peter L E M van Lent

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Articles 70
Citations 1849
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Recent Articles
11.
Vullings J, Vago J, Waterborg C, Thurlings R, Koenders M, van Lent P, et al.
J Immunol Res . 2020 Sep; 2020:9690832. PMID: 32964059
Objective: To investigate the role of TAM receptors in rheumatoid arthritis (RA) by determining synovial tissue TAM receptor expression, synovial fluid levels of soluble TAM receptors, and the relationship between...
12.
Arntz O, Pieters B, van Lent P, Koenders M, van der Kraan P, van de Loo F
PLoS One . 2020 Jul; 15(7):e0236508. PMID: 32726333
Extracellular vesicles (EVs) are cell membrane-derived phospholipid bilayer nanostructures that contain bioactive proteins, enzymes, lipids and polymers of nucleotides. They play a role in intercellular communication and are present in...
13.
Ascone G, Cao Y, Jansen I, Di Ceglie I, van den Bosch M, Blom A, et al.
Int J Mol Sci . 2020 May; 21(11). PMID: 32471111
Recently, it was shown that interleukin-1β (IL-1β) has diverse stimulatory effects on different murine long bone marrow osteoclast precursors (OCPs) in vitro. In this study, interleukin-1 receptor antagonist deficient ()...
14.
de Korte A, Aquarius R, Vogl T, Roth J, Bartels R, Boogaarts H, et al.
J Neurointerv Surg . 2020 Apr; 12(11):1117-1121. PMID: 32332055
Background: Inflammation-related factors might give further insight into the pathophysiology of vessel wall inflammation and intracranial aneurysm (IA) rupture. One of these factors is the protein complex S100A8/A9, which is...
15.
Rogier R, Ederveen T, Wopereis H, Hartog A, Boekhorst J, van Hijum S, et al.
PLoS One . 2020 Jan; 14(12):e0227517. PMID: 31891648
[This corrects the article DOI: 10.1371/journal.pone.0219366.].
16.
Pieters B, Cappariello A, van den Bosch M, van Lent P, Teti A, van de Loo F
Front Immunol . 2019 Aug; 10:1901. PMID: 31440259
Extracellular vesicles are a heterogeneous group of cell-derived membranous structures, which facilitate intercellular communication. Recent studies have highlighted the importance of extracellular vesicles in bone homeostasis, as mediators of crosstalk...
17.
Rogier R, Ederveen T, Wopereis H, Hartog A, Boekhorst J, van Hijum S, et al.
PLoS One . 2019 Jul; 14(7):e0219366. PMID: 31283798
The intestinal microbiome is perturbed in patients with new-onset and chronic autoimmune inflammatory arthritis. Recent studies in mouse models suggest that development and progression of autoimmune arthritis is highly affected...
18.
van Dalen S, Blom A, Walgreen B, Sloetjes A, Helsen M, Geven E, et al.
Front Immunol . 2019 Jun; 10:1075. PMID: 31191517
Injection of adipose-derived mesenchymal stromal cells (ASCs) into murine knee joints after induction of inflammatory collagenase-induced osteoarthritis (CiOA) reduces development of joint pathology. This protection is only achieved when ASCs...
19.
Di Ceglie I, Kruisbergen N, van den Bosch M, van Lent P
Rheumatology (Oxford) . 2019 Jun; 58(8):1331-1343. PMID: 31180451
Bone erosion is one of the central hallmarks of RA and is caused by excessive differentiation and activation of osteoclasts. Presence of autoantibodies in seropositive arthritis is associated with radiographic...
20.
Ascone G, Di Ceglie I, van den Bosch M, Kruisbergen N, Walgreen B, Sloetjes A, et al.
Clin Exp Rheumatol . 2019 May; 37(6):983-993. PMID: 31074720
Objectives: In this study, we used hypercholesterolaemic apolipoprotein E-deficient (Apoe-/-) mice to investigate LDL/oxLDL effect on synovial inflammation and cartilage destruction during antigen-induced arthritis (AIA). Further, as macrophage FcγRs are...