Peter J Stambrook
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Explore the profile of Peter J Stambrook including associated specialties, affiliations and a list of published articles.
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55
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1235
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Recent Articles
1.
Fu J, Ling J, Li C, Tsai C, Yin W, Hou J, et al.
Nat Commun
. 2024 Apr;
15(1):3149.
PMID: 38605037
Pancreatic ductal adenocarcinoma (PDAC) develops through step-wise genetic and molecular alterations including Kras mutation and inactivation of various apoptotic pathways. Here, we find that development of apoptotic resistance and metastasis...
2.
Kraljevic Pavelic S, Micek V, Bobinac D, Bazdulj E, Gianoncelli A, Krpan D, et al.
Exp Biol Med (Maywood)
. 2020 Nov;
246(5):529-537.
PMID: 33183068
The severity of osteoporosis in humans manifests in its high incidence and by its complications that diminish quality of life. A societal consequence of osteoporosis is the substantial burden that...
3.
Che L, Alavattam K, Stambrook P, Namekawa S, Du C
Cell Death Differ
. 2020 Mar;
27(8):2402-2416.
PMID: 32139899
BRUCE is a DNA damage response protein that promotes the activation of ATM and ATR for homologous recombination (HR) repair in somatic cells, making BRUCE a key protector of genomic...
4.
Huang W, Liang J, Feng Y, Jia Z, Jiang L, Cai W, et al.
Exp Cell Res
. 2018 May;
371(1):20-30.
PMID: 29842877
Although resident cardiac stem cells have been reported, regeneration of functional cardiomyocytes (CMs) remains a challenge. The present study identifies an alternative progenitor source for CM regeneration without the need...
5.
Huang W, Feng Y, Liang J, Yu H, Wang C, Wang B, et al.
Nat Commun
. 2018 Feb;
9(1):700.
PMID: 29453456
The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult CMs, partially due to their withdrawal...
6.
Nagel Z, Engelward B, Brenner D, Begley T, Sobol R, Bielas J, et al.
Mutat Res
. 2017 May;
800-802:14-28.
PMID: 28458064
The rise of advanced technologies for characterizing human populations at the molecular level, from sequence to function, is shifting disease prevention paradigms toward personalized strategies. Because minimization of adverse outcomes...
7.
Stambrook P, Maher J, Farzaneh F
Mol Cancer Res
. 2017 Mar;
15(6):635-650.
PMID: 28356330
The current concepts and practice of cancer immunotherapy evolved from classical experiments that distinguished "self" from "non-self" and the finding that humoral immunity is complemented by cellular immunity. Elucidation of...
8.
Lozada E, Andrysik Z, Yin M, Redilla N, Rice K, Stambrook P
Oncotarget
. 2016 Mar;
7(15):20425-39.
PMID: 26967250
The dual specificity phosphatase Cdc25A is a key regulator of the cell cycle that promotes cell cycle progression by dephosphorylating and activating cyclin-dependent kinases. In response to genotoxicants, Cdc25A undergoes...
9.
Michel D, Mun K, Ho C, Stambrook P
Exp Biol Med (Maywood)
. 2016 Feb;
241(6):603-10.
PMID: 26843517
Polo-like kinase 3 (Plk3) is best known for its involvement in cell cycle checkpoint regulation following exposure to cytotoxicants or induction of DNA damage. Yet, Plk3 has also been implicated...
10.
Mamrosh J, Lee J, Wagner M, Stambrook P, Whitby R, Sifers R, et al.
Elife
. 2015 Jul;
4:e10084.
PMID: 26205891
No abstract available.