Peter J McCormick
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Explore the profile of Peter J McCormick including associated specialties, affiliations and a list of published articles.
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90
Citations
2376
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Recent Articles
1.
Chen H, Highland H, Frankel E, Scartozzi A, Zhang X, Roshani R, et al.
Cell Genom
. 2025 Mar;
5(3):100784.
PMID: 40043711
Polygenic severe obesity (body mass index [BMI] ≥40 kg/m) has increased, especially in Hispanic/Latino populations, yet we know little about the underlying mechanistic pathways. We analyzed whole-blood multiomics data to...
2.
Farooq Z, Delre P, Iliadis S, Mangiatordi G, Contino M, Howell L, et al.
ACS Pharmacol Transl Sci
. 2025 Feb;
8(2):423-434.
PMID: 39974643
Emerging evidence has demonstrated that cannabinoid receptor 2 (CB) is involved in a number of diseases, such as neurodegenerative disorders and various types of cancer, making it an attractive pharmacological...
3.
Peri L, Matzov D, Huxley D, Rainish A, Fierro F, Sapir L, et al.
Nat Commun
. 2024 Nov;
15(1):9991.
PMID: 39557861
Bitter taste receptors (TAS2Rs), a subfamily of G-protein coupled receptors (GPCRs) expressed orally and extraorally, elicit signaling in response to a large set of tastants. Among 25 functional TAS2Rs encoded...
4.
Baker J, Sloan E, Pfleger K, Pfleger K, McCormick P, Salmeron C, et al.
Function (Oxf)
. 2024 Nov;
6(1).
PMID: 39547938
No abstract available.
5.
Yang T, Li J, Cheng X, Lu Q, Farooq Z, Fu Y, et al.
J Struct Biol
. 2024 Aug;
216(3):108117.
PMID: 39153560
The complement system is a complex network of proteins that plays a crucial role in the innate immune response. One important component of this system is the C5a-C5aR1 complex, which...
6.
Matsingos C, Howell L, McCormick P, Fornili A
J Mol Biol
. 2024 Jun;
436(16):168688.
PMID: 38936694
GPR68 is a proton-sensing G-protein Coupled Receptor (GPCR) involved in a variety of physiological processes and disorders including neoplastic pathologies. While GPR68 and few other GPCRs have been shown to...
7.
Kosar M, Sarott R, Sykes D, Viray A, Vitale R, Tomasevic N, et al.
ACS Cent Sci
. 2024 May;
10(5):956-968.
PMID: 38799662
We report a blueprint for the rational design of G protein coupled receptor (GPCR) ligands with a tailored functional response. The present study discloses the structure-based design of cannabinoid receptor...
8.
Cristovao-Ferreira S, Navarro G, Brugarolas M, Perez-Capote K, Vaz S, Fattorini G, et al.
Purinergic Signal
. 2024 Apr;
20(3):315-316.
PMID: 38671309
No abstract available.
9.
Yu B, Lu Q, Li J, Cheng X, Hu H, Li Y, et al.
J Biol Chem
. 2024 Apr;
300(6):107288.
PMID: 38636662
HCN channels are important for regulating heart rhythm and nerve activity and have been studied as potential drug targets for treating depression, arrhythmia, nerve pain, and epilepsy. Despite possessing unique...
10.
Wang D, Xiang Q, Hu X, Zhang Y, Wu L, Zhang Z, et al.
Virology
. 2023 Nov;
589:109925.
PMID: 37984151
SARS-CoV-2 and its variants continue to threaten public health. Nanobodies that block the attachment of the RBD to host cell angiotensin-converting enzyme 2 (ACE2) represent promising drug candidates. In this...