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Peter H Dube

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Articles 38
Citations 1091
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Recent Articles
1.
Wiscovitch-Russo R, Ibanez-Prada E, Serrano-Mayorga C, Sievers B, Engelbride M, Padmanabhan S, et al.
Crit Care . 2023 Apr; 27(1):155. PMID: 37081485
Background: The mechanisms used by SARS-CoV-2 to induce major adverse cardiac events (MACE) are unknown. Thus, we aimed to determine if SARS-CoV-2 can induce necrotic cell death to promote MACE...
2.
Wiscovitch-Russo R, Ibanez-Prada E, Serrano-Mayorga C, Sievers B, Engelbride M, Padmanabhan S, et al.
Res Sq . 2023 Jan; PMID: 36711834
Background The mechanisms used by SARS-CoV-2 to induce major adverse cardiac events (MACE) are unknown. Thus, we aimed to determine if SARS-CoV-2 can infect the heart to kill cardiomyocytes and...
3.
Ma H, Zhang X, Zheng P, Dube P, Zeng W, Chen S, et al.
Cell Res . 2022 Jul; 32(9):831-842. PMID: 35906408
SARS-CoV-2 variants with adaptive mutations have continued to emerge, causing fresh waves of infection even amongst vaccinated population. The development of broad-spectrum antivirals is thus urgently needed. We previously developed...
4.
Cantwell A, Singh H, Platt M, Yu Y, Lin Y, Ikeno Y, et al.
J Virol . 2021 Jul; 95(20):e0101021. PMID: 34319784
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is poorly understood due to a lack of an animal model that recapitulates severe human disease. Here, we report...
5.
Lin Y, Platt M, Gilley R, Brown D, Dube P, Yu Y, et al.
Circ Res . 2021 Jan; 128(5):570-584. PMID: 33501852
Rationale: Patients with and without cardiovascular diseases have been shown to be at risk of influenza-mediated cardiac complications. Recent clinical reports support the notion of a direct link between laboratory-confirmed...
6.
She L, Barrera G, Yan L, Alanazi H, Brooks E, Dube P, et al.
JCI Insight . 2021 Jan; 6(3). PMID: 33400692
2'3'-cGAMP is known as a nonclassical second messenger and small immune modulator that possesses potent antitumor and antiviral activities via inducing the stimulator of IFN genes-mediated (STING-mediated) signaling pathway. However,...
7.
Gonzalez-Juarbe N, Riegler A, Jureka A, Gilley R, Brand J, Trombley J, et al.
Cell Rep . 2020 Aug; 32(8):108062. PMID: 32846120
Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated...
8.
She L, Alanazi H, Yan L, Brooks E, Dube P, Xiang Y, et al.
PLoS One . 2020 Jul; 15(7):e0236744. PMID: 32730309
Repeated exposures to environmental allergens in susceptible individuals drive the development of type 2 inflammatory conditions such as asthma, which have been traditionally considered to be mainly mediated by Th2...
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Gilley R, Dube P
Oncotarget . 2020 Mar; 11(7):740-754. PMID: 32133048
Melanoma continues to be a significant health concern worldwide despite recent improvements in treatment. Unlike many other prominent cancers, melanoma incidence in both men and women increased over the past...