Peter Guttorp
Overview
Explore the profile of Peter Guttorp including associated specialties, affiliations and a list of published articles.
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10
Citations
322
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Recent Articles
1.
Xu J, Wang Y, Guttorp P, Abkowitz J
Blood Adv
. 2018 Oct;
2(20):2637-2645.
PMID: 30327372
Stochastic simulation has played an important role in understanding hematopoiesis, but implementing and interpreting mathematical models requires a strong statistical background, often preventing their use by many clinical and translational...
2.
Andersson C, Guttorp P, Sarkka A
Stat Med
. 2016 Jun;
35(24):4427-4442.
PMID: 27311590
Epidermal nerve fibre (ENF) density and morphology are used to study small fibre involvement in diabetic, HIV, chemotherapy induced and other neuropathies. ENF density and summed length of ENFs per...
3.
Xu J, Guttorp P, Kato-Maeda M, Minin V
Biometrics
. 2015 Jul;
71(4):1009-21.
PMID: 26148963
Continuous-time birth-death-shift (BDS) processes are frequently used in stochastic modeling, with many applications in ecology and epidemiology. In particular, such processes can model evolutionary dynamics of transposable elements-important genetic markers...
4.
Fong Y, Guttorp P, Abkowitz J
Ann Appl Stat
. 2013 Oct;
3(4):1696-1709.
PMID: 24078859
Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly observed and measured. Previously we modeled feline hematopoiesis using a two-compartment...
5.
Catlin S, Busque L, Gale R, Guttorp P, Abkowitz J
Blood
. 2011 Feb;
117(17):4460-6.
PMID: 21343613
Hematopoietic stem cells (HSCs) replicate (self-renew) to create 2 daughter cells with capabilities equivalent to their parent, as well as differentiate, and thus can both maintain and restore blood cell...
6.
Shepherd B, Kiem H, Lansdorp P, Dunbar C, Aubert G, Larochelle A, et al.
Blood
. 2007 May;
110(6):1806-13.
PMID: 17526860
Little is known about the behavior of hematopoietic stem cells (HSCs) in primates because direct observations and competitive-repopulation assays are not feasible. Therefore, we used 2 different and independent experimental...
7.
Catlin S, Guttorp P, Abkowitz J
Blood
. 2005 Jul;
106(8):2688-92.
PMID: 16002428
To study clonal evolution in myeloproliferative disorders, we used stochastic models of hematopoiesis for mouse and cat, species for which the in vivo kinetics of hematopoietic stem cells (HSCs) have...
8.
Shepherd B, Guttorp P, Lansdorp P, Abkowitz J
Exp Hematol
. 2004 Nov;
32(11):1040-50.
PMID: 15539081
Objective: To study in vivo behavior of hematopoietic stem cells (HSC). Materials And Methods: Behavior of HSC is difficult to study because one cannot observe and track cells within the...
9.
Abkowitz J, Golinelli D, Guttorp P
Mol Ther
. 2004 Apr;
9(4):566-76.
PMID: 15093187
Data in mice suggest that in vivo selection strategies will expand the numbers of transduced hematopoietic stem cells (HSC) to levels sufficient for clinical therapies, and it is argued that...
10.
Abkowitz J, Catlin S, McCallie M, Guttorp P
Blood
. 2002 Sep;
100(7):2665-7.
PMID: 12239184
Humans and larger mammals require more blood cells per lifetime than mice because of their larger size and longer life expectancy. To investigate this evolutionary adaptation, we calculated the total...