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Peter Ganz

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Articles 170
Citations 6241
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Recent Articles
1.
Chadwick J, Hinterberg M, Asselbergs F, Biegel H, Boersma E, Cappola T, et al.
Circ Heart Fail . 2025 Mar; :e011208. PMID: 40052265
Background: We derived and validated proteomic risk scores (PRSs) for heart failure (HF) prognosis that provide absolute risk estimates for all-cause mortality within 1 year. Methods: Plasma samples from individuals...
2.
Raffield L, Nicholas J, Nicholas J, Katz D, Tahir U, Katz D, et al.
Res Sq . 2025 Feb; PMID: 39989965
Measures from affinity-proteomics platforms often correlate poorly, challenging interpretation of protein associations with genetic variants (pQTL) and phenotypes. Here, we examined 2,157 proteins measured on both SomaScan 7k and Olink...
3.
Sedaghat S, Park S, Walker R, Wang S, Liu J, Hughes T, et al.
Res Sq . 2025 Jan; PMID: 39877085
Background: Biological age can be quantified by composite proteomic scores, called aging clocks. We investigated whether biological age acceleration (a discrepancy between chronological and biological age) in midlife and late-life...
4.
Wang S, Rao Z, Li A, Blaes A, Blaha M, Coresh J, et al.
medRxiv . 2025 Jan; PMID: 39830250
Background: To measure the aging process before a cancer diagnosis, we developed the first cancer-specific proteomic aging clock (CaPAC) and examined its association with cancer risk in the Atherosclerosis Risk...
5.
Ji Y, Zhang M, Wang W, Norby F, Eaton A, Inciardi R, et al.
Circulation . 2024 Nov; 151(6):356-367. PMID: 39569504
Background: Coagulation factor XI (FXI) inhibitors are a promising and novel class of anticoagulants, but a recent animal study found that FXI inhibition exacerbated diastolic dysfunction and heart failure (HF)....
6.
Yu Z, Vromman A, Nguyen N, Schuermans A, Rentz T, Vellarikkal S, et al.
bioRxiv . 2024 Nov; PMID: 39554199
Plasma proteomic profiles associated with subclinical somatic mutations in blood cells may offer novel insights into downstream clinical consequences. Here, we explore such patterns in clonal hematopoiesis of indeterminate potential...
7.
Deo R, Dubin R, Ren Y, Wang J, Feldman H, Shou H, et al.
J Am Soc Nephrol . 2024 Sep; 36(2):231-241. PMID: 39325542
No abstract available.
8.
Wang S, Rao Z, Cao R, Blaes A, Coresh J, Deo R, et al.
PLoS Med . 2024 Sep; 21(9):e1004464. PMID: 39316596
Background: Biological age may be estimated by proteomic aging clocks (PACs). Previous published PACs were constructed either in smaller studies or mainly in white individuals, and they used proteomic measures...
9.
Kohler T, Kloner R, Rosen R, Burnett A, Blaha M, Ganz P, et al.
Mayo Clin Proc . 2024 Aug; 99(9):1500-1517. PMID: 39115509
The Princeton Consensus (Expert Panel) Conference is a multispecialty collaborative symposium dedicated to optimizing sexual function and preserving cardiovascular health. The Fourth Princeton Consensus Conference was convened on March 10-11,...
10.
Wang S, Rao Z, Blaes A, Coresh J, Joshu C, Pankow J, et al.
medRxiv . 2024 Jul; PMID: 39040202
Background: We constructed a new proteomic aging clock (PAC) and computed the published Lehallier's PAC to estimate biological age. We tested PACs' associations with mortality in longer-term cancer survivors and...