Peter E Kima
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Explore the profile of Peter E Kima including associated specialties, affiliations and a list of published articles.
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31
Citations
559
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Recent Articles
21.
Kima P, Rasche M
Biochem Mol Biol Educ
. 2011 Jun;
32(2):115-9.
PMID: 21706704
PCR has revolutionized many aspects of biochemistry and molecular biology research. In the following exercise, students learn PCR by isolating their own DNA, amplifying specific segments of the X and...
22.
Kima P, Bonilla J, Cho E, Ndjamen B, Canton J, Leal N, et al.
PLoS Negl Trop Dis
. 2010 Oct;
4(10).
PMID: 20957202
Although Leishmania parasites have been shown to modulate their host cell's responses to multiple stimuli, there is limited evidence that parasite molecules are released into infected cells. In this study,...
23.
Ndjamen B, Kang B, Hatsuzawa K, Kima P
Cell Microbiol
. 2010 May;
12(10):1480-94.
PMID: 20497181
Macrophages that express representative endoplasmic reticulum (ER) molecules tagged with green fluorescence protein were generated to assess the recruitment of ER molecules to Leishmania parasitophorous vacuoles (PVs). More than 90%...
24.
Ruhland A, Kima P
Exp Parasitol
. 2009 Feb;
122(1):28-36.
PMID: 19186178
Infection of macrophages with Leishmania parasites does not result in the production of IL-12. In addition, infection with Leishmania suppresses IL-12 production elicited by otherwise potent activators of IL-12. We...
25.
Kima P
Int J Parasitol
. 2007 Jun;
37(10):1087-96.
PMID: 17543969
Leishmania are dimorphic protozoan parasites that live as flagellated forms in the gut of their sandfly vector and as aflagellated forms in their mammalian hosts. Although both parasite forms can...
26.
Ruhland A, Leal N, Kima P
Cell Microbiol
. 2006 Aug;
9(1):84-96.
PMID: 16889626
Previous reports have shown that cells infected with promastigotes of some Leishmania species are resistant to the induction of apoptosis. This would suggest that either parasites elaborate factors that block...
27.
Pham N, Mouriz J, Kima P
Infect Immun
. 2005 Nov;
73(12):8322-33.
PMID: 16299330
Whereas infections of macrophages by promastigote forms of Leishmania mexicana pifanoi induce the production of superoxide, infections by amastigotes barely induce superoxide production. Several approaches were employed to gain insight...
28.
Kima P, Dunn W
Microb Pathog
. 2005 Mar;
38(4):139-45.
PMID: 15797809
We have developed a simple scheme for the isolation of parasitophorous vacuoles (PVs) that harbor Leishmania parasites. This scheme exploits the observation that PVs display endoplasmic reticulum molecules, including the...
29.
Colmenares M, Kima P, Samoff E, Soong L, McMahon-Pratt D
Infect Immun
. 2003 May;
71(6):3172-82.
PMID: 12761096
Previous studies have demonstrated that protection against New World leishmaniasis caused by Leishmania amazonensis can be elicited by immunization with the developmentally regulated Leishmania amastigote antigen, P-8. In this study,...
30.
Leal N, Park S, Kima P, Bobik T
J Biol Chem
. 2003 Jan;
278(11):9227-34.
PMID: 12514191
In humans, deficiencies in coenzyme B12-dependent methylmalonyl-CoA mutase (MCM) lead to methylmalonyl aciduria, a rare disease that is often fatal in newborns. Such deficiencies can result from inborn errors in...