Peter E J Bols
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Explore the profile of Peter E J Bols including associated specialties, affiliations and a list of published articles.
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29
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400
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Recent Articles
11.
Marei W, Van Raemdonck G, Baggerman G, Bols P, Leroy J
Sci Rep
. 2019 Mar;
9(1):3673.
PMID: 30842615
Maternal lipolytic metabolic disorders result in a lipotoxic microenvironment in the ovarian follicular fluid (FF) which deteriorates oocyte quality. Although cellular stress response mechanisms are well defined in somatic cells,...
12.
Bus A, Van Hoeck V, Langbeen A, Leroy J, Bols P
J Assist Reprod Genet
. 2018 May;
35(7):1187-1199.
PMID: 29797286
Purpose: Individual follicle cryopreservation techniques, without hydrogel support, are labor-intensive and a substantial proportion of isolated follicles are lost during handling and after warming. Therefore, the viability and morphology of...
13.
Jordaens L, Van Hoeck V, De Bie J, Berth M, Marei W, Desmet K, et al.
Reprod Biol
. 2017 May;
17(3):281-284.
PMID: 28551031
We investigated whether and to which extent plasma non-esterified fatty acids (NEFAs) are reflected in oviduct fluid (OF) using an improved ex vivo flushing method. OF and plasma NEFA concentrations...
14.
Marei W, De Bie J, Mohey-Elsaeed O, Wydooghe E, Bols P, Leroy J
Biol Reprod
. 2017 May;
96(6):1181-1196.
PMID: 28520897
Elevated concentrations of free fatty acids (FFAs), predominantly palmitic, stearic, and oleic acids (PSO), exert detrimental effects on oocyte developmental competence. This study examined the effects of omega-3 alpha-linolenic acid...
15.
Marei W, Arias Alvarez M, Van Hoeck V, Gutierrez-Adan A, Bols P, Leroy J
Reprod Fertil Dev
. 2016 Nov;
29(9):1856-1867.
PMID: 27832581
The present study examined whether the effects of dietary-induced hyperlipidaemia on preimplantation embryo development depend on the predominant fatty acid (FA) type in the diet. In a combined in vivo-in...
16.
Jorssen E, Vergauwen L, Goossens K, Hagenaars A, Van Poucke M, Petro E, et al.
Altern Lab Anim
. 2015 May;
43(2):89-100.
PMID: 25995012
Developmental toxicity testing could greatly benefit from the availability of an in vitro alternative model based on the use of animal embryos that have better human-like physiology than the currently-used...
17.
Langbeen A, De Porte H, Bartholomeus E, Leroy J, Bols P
Theriogenology
. 2015 May;
84(4):477-89.
PMID: 25981885
Recent increases in the number of successful cancer treatments have stimulated interest in fertility preservation strategies in women of reproductive age and in prepubertal girls. However, research on the application...
18.
Leroy J, Valckx S, Jordaens L, De Bie J, Desmet K, Van Hoeck V, et al.
Reprod Fertil Dev
. 2015 Feb;
27(4):693-703.
PMID: 25690396
Although fragmented and sometimes inconsistent, the proof of a vital link between the importance of the physiological status of the mother and her subsequent reproductive success is building up. High-yielding...
19.
Valckx S, Van Hoeck V, Arias-Alvarez M, Maillo V, Lopez-Cardona A, Gutierrez-Adan A, et al.
Fertil Steril
. 2014 Sep;
102(6):1769-76.e1.
PMID: 25256931
Objective: To study how long-term elevated non-esterified fatty acid (NEFA) concentrations, typical in metabolic disorders such as obesity or type 2 diabetes, affect murine follicular development, follicle quality, and subsequent...
20.
Van Hoeck V, Bols P, Binelli M, Leroy J
Anim Reprod Sci
. 2014 Aug;
149(1-2):19-29.
PMID: 25129636
Reproductive performance is increasingly considered as a 'barometer' of general well-being of the mother. A normal maternal 'metabolic health' status is essential to safeguard successful ovulation, conception and further embryo...