Isabel Pintelon
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Explore the profile of Isabel Pintelon including associated specialties, affiliations and a list of published articles.
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109
Citations
1296
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Recent Articles
1.
Vasilkovska T, Verschuuren M, Pustina D, van den Berg M, Van Audekerke J, Pintelon I, et al.
Clin Transl Med
. 2024 Oct;
14(10):e70055.
PMID: 39422700
Background: Huntington's disease (HD) is marked by irreversible loss of neuronal function for which currently no availability for disease-modifying treatment exists. Advances in the understanding of disease progression can aid...
2.
Neutel C, Wesley C, van Loo C, Civati C, Mertens F, Zurek M, et al.
Commun Biol
. 2024 Oct;
7(1):1241.
PMID: 39358413
Calciprotein particles (CPPs) are an endogenous buffering system, clearing excessive amounts of Ca and PO from the circulation and thereby preventing ectopic mineralization. CPPs circulate as primary CPPs (CPP1), which...
3.
Peleman C, Hellemans S, Veeckmans G, Arras W, Zheng H, Koeken I, et al.
Cell Death Differ
. 2024 Jul;
31(9):1113-1126.
PMID: 39060422
There is an unmet clinical need for pharmacologic treatment for metabolic dysfunction-associated steatotic liver disease (MASLD). Hepatocyte cell death is a hallmark of this highly prevalent chronic liver disease, but...
4.
Hirschberg Y, Boonen K, Schildermans K, van Dam A, Pintelon I, Vandendriessche C, et al.
J Extracell Biol
. 2024 Jun;
1(9):e55.
PMID: 38938772
Extracellular vesicles (EVs) are suggested to have a role in the progression of neurodegeneration, and are able to transmit pathological proteins from one cell to another. One of the biofluids...
5.
Xhonneux I, Marei W, Meulders B, Slootmans J, Pintelon I, Leroy J
PLoS One
. 2024 Jun;
19(6):e0305912.
PMID: 38935642
Diet-induced obesity reduces oocyte quality mainly by impacting oocyte mitochondrial functions. Moreover, maternal obesity is associated with mitochondrial dysfunction in oocytes of their adult offspring. However, these effects were reported...
6.
Penagos I, De Witte F, Rimaux T, Chevremont W, Pintelon I, Dewettinck K, et al.
Soft Matter
. 2024 Jun;
20(26):5071-5085.
PMID: 38887036
In the last decade, research has focused on examining the fundamental interactions occurring in triglycerides, aiming to comprehend the self-assembly of crystalline nanoplatelets (CNPs) and their role in forming larger...
7.
Tanc M, Filippi N, Van Rymenant Y, Grintsevich S, Pintelon I, Verschuuren M, et al.
J Med Chem
. 2024 Apr;
67(9):7068-7087.
PMID: 38656144
Fibroblast activation protein (FAP) is a very reliable biomarker for tissue remodeling. FAP has so far mainly been studied in oncology, but there is growing interest in the enzyme in...
8.
Vasilkovska T, Salajeghe S, Vanreusel V, Van Audekerke J, Verschuuren M, Hirschler L, et al.
J Biomed Sci
. 2024 Apr;
31(1):37.
PMID: 38627751
Background: Huntington's disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex. Alterations in the...
9.
Espadinha M, De Loose J, Corthaut S, Thys S, Van Rymenant Y, Verhulst E, et al.
Eur J Med Chem
. 2024 Apr;
270:116389.
PMID: 38593588
Dipeptidyl peptidases (DPP) 8 and 9 are intracellular serine proteases that play key roles in various biological processes and recent findings highlight DPP8 and DPP9 as potential therapeutic targets for...
10.
Marei W, Mohey-Elsaeed O, Pintelon I, Leroy J
J Assist Reprod Genet
. 2023 Dec;
41(2):371-383.
PMID: 38146030
Purpose: Oxidative stress and mitochondrial dysfunction play central roles in reduced oocyte quality and infertility in obese patients. Mitochondria-targeted treatments containing co-enzyme Q10 such as mitoquinone (MitoQ) can increase mitochondrial...