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Peter E Clayton

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Articles 84
Citations 1695
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Recent Articles
1.
Maghnie M, Ranke M, Geffner M, Vlachopapadopoulou E, Ibanez L, Carlsson M, et al.
J Clin Endocrinol Metab . 2023 Feb; 108(6):e356-e357. PMID: 36721915
No abstract available.
2.
Maghnie M, Ranke M, Geffner M, Vlachopapadopoulou E, Ibanez L, Carlsson M, et al.
J Clin Endocrinol Metab . 2022 Sep; 107(12):3287-3301. PMID: 36102184
Context: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with recombinant human growth hormone (rhGH) in real-world settings. Objective: This work aimed to...
3.
Evans B, Hurlstone A, Clayton P, Stevens A, Shiels H
Curr Res Physiol . 2022 May; 5:216-223. PMID: 35637870
Respirometry, based on oxygen uptake, is commonly employed for measuring metabolic rate. There is a growing need for metabolic rate measurements suitable for developmental studies, particularly in , where many...
4.
Boguszewski M, Boguszewski C, Chemaitilly W, Cohen L, Gebauer J, Higham C, et al.
Eur J Endocrinol . 2022 Mar; 186(6):P35-P52. PMID: 35319491
Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been studied extensively. Experimental studies showing the permissive role of GH/insulin-like growth factor 1...
5.
Parsons S, Stevens A, Whatmore A, Clayton P, Murray P
J Endocr Soc . 2022 Feb; 6(3):bvac006. PMID: 35178492
Context: Single-nucleotide polymorphisms (SNPs) in have been associated with idiopathic short stature (ISS) and adult height. Objective: This study sought to (a) characterize the phenotype of ISS patients and their...
6.
Buonocore F, Maharaj A, Qamar Y, Koehler K, Suntharalingham J, Chan L, et al.
J Endocr Soc . 2021 Jul; 5(8):bvab086. PMID: 34258490
Context: Although primary adrenal insufficiency (PAI) in children and young people is often due to congenital adrenal hyperplasia (CAH) or autoimmunity, other genetic causes occur. The relative prevalence of these...
7.
Lin Q, Jiang Y, Wang G, Sun W, Dong S, Deng Y, et al.
Appetite . 2021 Feb; 162:105174. PMID: 33636216
Previous studies have suggested that infant rapid weight change can be associated with an increased weight later in life. However, the weight change trajectory in early life over time and...
8.
Vaz F, McDermott J, Alders M, Wortmann S, Kolker S, Pras-Raves M, et al.
Brain . 2019 Oct; 142(11):3382-3397. PMID: 31637422
CTP:phosphoethanolamine cytidylyltransferase (ET), encoded by PCYT2, is the rate-limiting enzyme for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway. Phosphatidylethanolamine is one of the most abundant membrane lipids and is particularly enriched...
9.
Murray P, Stevens A, De Leonibus C, Koledova E, Chatelain P, Clayton P
JCI Insight . 2018 Apr; 3(7). PMID: 29618660
Background: The effect of gene expression data on diagnosis remains limited. Here, we show how diagnosis and classification of growth hormone deficiency (GHD) can be achieved from a single blood...
10.
Chatterjee S, Shapiro L, Rose S, Mushtaq T, Clayton P, Ten S, et al.
Eur J Endocrinol . 2018 Mar; 178(5):481-489. PMID: 29500309
Background: Patients with homozygous intronic pseudoexon GH receptor () mutations (6Ψ) have growth hormone insensitivity (GHI) (growth failure, IGF1 deficiency and normal/elevated serum GH). We report 9 patients in addition...