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Adam Stevens

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Articles 68
Citations 1169
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Recent Articles
1.
Cuvertino S, Garner T, Martirosian E, Walusimbi B, Kimber S, Banka S, et al.
Brief Bioinform . 2024 Dec; 26(1). PMID: 39701600
Complex direct and indirect relationships between multiple variables, termed higher order interactions (HOIs), are characteristics of all natural systems. Traditional differential and network analyses fail to account for the omic...
2.
Soni S, Stevens A, Batra G, Heazell A
Placenta . 2024 Oct; 158:48-56. PMID: 39368233
The normal development of the placenta is vital for fetal growth and a healthy pregnancy outcome. Delayed villous maturation (DVM) is a placental lesion that has been implicated in stillbirth....
3.
Ripley D, Garner T, Stevens A
Comp Biochem Physiol Part D Genomics Proteomics . 2024 Jul; 52:101287. PMID: 38972179
Typical 'omic analyses reduce complex biological systems to simple lists of supposedly independent variables, failing to account for changes in the wider transcriptional landscape. In this commentary, we discuss the...
4.
Garner T, Clayton P, Hojby M, Murray P, Stevens A
J Clin Endocrinol Metab . 2023 Dec; 109(5):1214-1221. PMID: 38066644
Context: The pretreatment blood transcriptome predicts growth response to daily growth hormone (GH) therapy with high accuracy. Objective: Investigate response prediction using pretreatment transcriptome in children with GH deficiency (GHD)...
5.
West P, Tontini C, Atmoko H, Kiss O, Garner T, Bahri R, et al.
Cells . 2023 Sep; 12(17). PMID: 37681909
Mast cells (MCs) contribute to skin inflammation. In psoriasis, the activation of cutaneous neuroimmune networks commonly leads to itch. To dissect the unique contribution of MCs to the cutaneous neuroinflammatory...
6.
Ripley D, Garner T, Hook S, Verissimo A, Grunow B, Moritz T, et al.
Sci Total Environ . 2023 Aug; 902:165954. PMID: 37536606
Exposure to elevated temperatures during embryogenesis can influence the plasticity of tissues in later life. Despite these long-term changes in plasticity, few differentially expressed genes are ever identified, suggesting that...
7.
Garner T, Wangsaputra I, Whatmore A, Clayton P, Stevens A, Murray P
Front Endocrinol (Lausanne) . 2023 Mar; 14:1026187. PMID: 36864831
Background: Gene expression (GE) data have shown promise as a novel tool to aid in the diagnosis of childhood growth hormone deficiency (GHD) when comparing GHD children to normal children....
8.
Evans B, Hurlstone A, Clayton P, Stevens A, Shiels H
Curr Res Physiol . 2022 May; 5:216-223. PMID: 35637870
Respirometry, based on oxygen uptake, is commonly employed for measuring metabolic rate. There is a growing need for metabolic rate measurements suitable for developmental studies, particularly in , where many...
9.
Lombardo S, Wangsaputra I, Menche J, Stevens A
Genes (Basel) . 2022 May; 13(5). PMID: 35627149
The early developmental phase is of critical importance for human health and disease later in life. To decipher the molecular mechanisms at play, current biomedical research is increasingly relying on...
10.
Ufuk A, Garner T, Stevens A, Latif A
Cancers (Basel) . 2022 Mar; 14(5). PMID: 35267606
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a five-year survival rate of <8%. PDAC is characterised by desmoplasia with an abundant extracellular matrix (ECM) rendering current therapies ineffective....