Peter Durda
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Explore the profile of Peter Durda including associated specialties, affiliations and a list of published articles.
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59
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1327
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Recent Articles
1.
Orchard P, Blackwell T, Kachuri L, Castaldi P, Cho M, Christenson S, et al.
medRxiv
. 2025 Mar;
PMID: 40034763
Most genetic variants associated with complex traits and diseases occur in non-coding genomic regions and are hypothesized to regulate gene expression. To understand the genetics underlying gene expression variability, we...
2.
Raffield L, Nicholas J, Katz D, Nicholas J, Tahir U, Katz D, et al.
Res Sq
. 2025 Feb;
PMID: 39989965
Measures from affinity-proteomics platforms often correlate poorly, challenging interpretation of protein associations with genetic variants (pQTL) and phenotypes. Here, we examined 2,157 proteins measured on both SomaScan 7k and Olink...
3.
Zhang D, Gao B, Feng Q, Manichaikul A, Peloso G, Tracy R, et al.
HGG Adv
. 2024 Nov;
6(1):100383.
PMID: 39543875
Blood lipid traits are treatable and heritable risk factors for heart disease, a leading cause of mortality worldwide. Although genome-wide association studies (GWASs) have discovered hundreds of variants associated with...
4.
Anwar M, Highland H, Buchanan V, Graff M, Young K, Taylor K, et al.
Obesity (Silver Spring)
. 2024 Nov;
32(11):2024-2034.
PMID: 39497627
Objective: Individuals living with obesity are differentially susceptible to cardiometabolic diseases. We hypothesized that an integrative multi-omics approach might improve identification of subgroups of individuals with obesity who have distinct...
5.
Liu S, Zhu J, Zhong H, Wu C, Xue H, Darst B, et al.
Diabetologia
. 2024 Sep;
67(12):2754-2770.
PMID: 39349773
Aims/hypothesis: Several studies have reported associations between specific proteins and type 2 diabetes risk in European populations. To better understand the role played by proteins in type 2 diabetes aetiology...
6.
Tahir U, Barber J, Cruz D, Kars M, Deng S, Tuftin B, et al.
J Clin Invest
. 2024 Sep;
134(21).
PMID: 39316441
BACKGROUNDMost GWAS of plasma proteomics have focused on White individuals of European ancestry, limiting biological insight from other ancestry-enriched protein quantitative loci (pQTL).METHODSWe conducted a discovery GWAS of approximately 3,000...
7.
Peterson T, Lima J, Shah S, Bluemke D, Bertoni A, Liu Y, et al.
ESC Heart Fail
. 2024 Sep;
12(1):239-249.
PMID: 39263947
Aims: Proteomic profiling offers an expansive approach to biomarker discovery and mechanistic hypothesis generation for LV remodelling, a critical component of heart failure (HF). We sought to identify plasma proteins...
8.
Jones A, Patki A, Srinivasasainagendra V, Hidalgo B, Tiwari H, Limdi N, et al.
Sci Rep
. 2024 Jul;
14(1):17757.
PMID: 39085340
Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease. Epigenetic modifications, such as DNA...
9.
Wen J, Sun Q, Huang L, Zhou L, Doyle M, Ekunwe L, et al.
Genetics
. 2024 Jul;
228(1).
PMID: 39056362
Most gene expression and alternative splicing quantitative trait loci (eQTL/sQTL) studies have been biased toward European ancestry individuals. Here, we performed eQTL and sQTL analyses using TOPMed whole-genome sequencing-derived genotype...
10.
Jiang M, Gaynor S, Li X, Van Buren E, Stilp A, Buth E, et al.
Hum Mol Genet
. 2024 May;
33(16):1429-1441.
PMID: 38747556
Inflammation biomarkers can provide valuable insight into the role of inflammatory processes in many diseases and conditions. Sequencing based analyses of such biomarkers can also serve as an exemplar of...