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Peter Danilo Jr

Explore the profile of Peter Danilo Jr including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 989
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Recent Articles
11.
Shlapakova I, Nearing B, Lau D, Boink G, Danilo Jr P, Kryukova Y, et al.
Heart Rhythm . 2010 Aug; 7(12):1835-40. PMID: 20708103
Background: Biological pacemakers based on the HCN2 channel isoform respond to beta-adrenergic and muscarinic stimulation, suggesting a capacity to respond to autonomic input. Objective: The purpose of this study was...
12.
Coronel R, Lau D, Sosunov E, Janse M, Danilo Jr P, Anyukhovsky E, et al.
Heart Rhythm . 2010 Apr; 7(8):1104-10. PMID: 20385252
Background: Skeletal muscle sodium channel (Nav1.4) expression in border zone myocardium increases action potential upstroke velocity in depolarized isolated tissue. Because resting membrane potential in the 1-week canine infarct is...
13.
Ozgen N, Lau D, Shlapakova I, Sherman W, Feinmark S, Danilo Jr P, et al.
Heart Rhythm . 2010 Mar; 7(7):964-70. PMID: 20346417
Background: Left ventricular pacing (LVP) to induce cardiac memory (CM) in dogs results in a decreased transient outward K current (I(to)) and reduced mRNA and protein of the I(to) channel...
14.
Ozgen N, Guo J, Gertsberg Z, Danilo Jr P, Rosen M, Steinberg S
Mol Pharmacol . 2009 Jul; 76(4):896-902. PMID: 19620255
Reactive oxygen species (ROS) exert pleiotropic effects on a wide array of signaling proteins that regulate cellular growth and apoptosis. This study shows that long-term treatment with a low concentration...
15.
Lau D, Clausen C, Sosunov E, Shlapakova I, Anyukhovsky E, Danilo Jr P, et al.
Circulation . 2008 Dec; 119(1):19-27. PMID: 19103989
Background: In depolarized myocardial infarct epicardial border zones, the cardiac sodium channel (SCN5A) is largely inactivated, contributing to low action potential upstroke velocity (V(max)), slow conduction, and reentry. We hypothesized...
16.
Rosen M, Brink P, Cohen I, Danilo Jr P, Robinson R, Rosen A, et al.
J Interv Card Electrophysiol . 2008 Mar; 22(2):87-98. PMID: 18363088
The prevention and treatment of cardiac arrhythmias conferring major morbidity and mortality is far from optimal, and relies heavily on devices and drugs for the partial successes that have been...
17.
Plotnikov A, Bucchi A, Shlapakova I, Danilo Jr P, Brink P, Robinson R, et al.
Heart Rhythm . 2008 Feb; 5(2):282-8. PMID: 18242555
Background: A potential concern about biological pacemakers is their possible malfunction, which might create ventricular tachycardias (VTs). Objective: The purpose of this study was to test our hypothesis that should...
18.
Plotnikov A, Shlapakova I, Szabolcs M, Danilo Jr P, Lorell B, Potapova I, et al.
Circulation . 2007 Jul; 116(7):706-13. PMID: 17646577
Background: Biological pacemaking has been performed with viral vectors, human embryonic stem cells, and adult human mesenchymal stem cells (hMSCs) as delivery systems. Only with human embryonic stem cells are...
19.
Coronel R, Opthof T, Plotnikov A, Wilms-Schopman F, Shlapakova I, Danilo Jr P, et al.
Cardiovasc Res . 2007 Mar; 74(3):416-25. PMID: 17391659
Objective: The contribution of regional electrophysiologic heterogeneity to the T-wave changes of long-term cardiac memory (CM) is not known. We mapped activation and repolarization in dogs after induction of CM...
20.
Opthof T, Coronel R, Wilms-Schopman F, Plotnikov A, Shlapakova I, Danilo Jr P, et al.
Heart Rhythm . 2007 Mar; 4(3):341-8. PMID: 17341400
Background: The concept that the interval between the peak (T(peak)) and the end (T(end)) of the T wave (T(p-e)) is a measure of transmural dispersion of repolarization time is widely...