Peter C FitzGerald
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Explore the profile of Peter C FitzGerald including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1921
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0
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Recent Articles
1.
Vega-Sendino M, Olbrich T, Tillo D, Tran A, Domingo C, Franco M, et al.
Sci Adv
. 2021 Oct;
7(40):eabg8306.
PMID: 34597136
The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this period, little is known about the downstream effectors regulating...
2.
Olbrich T, Vega-Sendino M, Tillo D, Wu W, Zolnerowich N, Pavani R, et al.
Nat Commun
. 2021 Aug;
12(1):4856.
PMID: 34381034
Totipotent cells have the ability to generate embryonic and extra-embryonic tissues. Interestingly, a rare population of cells with totipotent-like potential, known as 2 cell (2C)-like cells, has been identified within...
3.
Assad N, Tillo D, Ray S, Dzienny A, FitzGerald P, Vinson C
ACS Omega
. 2021 Jun;
4(6):9904-9910.
PMID: 34151054
Previously, cooperative binding of the bZIP domain of CREB1 and the ETS domain of GABPα was observed for the composite DNA ETS ⇔ CRE motif ( ). Single nucleotide polymorphisms...
4.
Sun Z, Yakhnin A, FitzGerald P, Mclntosh C, Kashlev M
Nat Commun
. 2021 Feb;
12(1):906.
PMID: 33568644
Promoter-proximal pausing regulates eukaryotic gene expression and serves as checkpoints to assemble elongation/splicing machinery. Little is known how broadly this type of pausing regulates transcription in bacteria. We apply nascent...
5.
Yakhnin A, FitzGerald P, McIntosh C, Yakhnin H, KIreeva M, Turek-Herman J, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(35):21628-21636.
PMID: 32817529
Transcription is punctuated by RNA polymerase (RNAP) pausing. These pauses provide time for diverse regulatory events that can modulate gene expression. Transcription elongation factors dramatically affect RNAP pausing in vitro,...
6.
Pastrana D, Peretti A, Welch N, Borgogna C, Olivero C, Badolato R, et al.
mSphere
. 2018 Dec;
3(6).
PMID: 30541782
Several immunodeficiencies are associated with high susceptibility to persistent and progressive human papillomavirus (HPV) infection leading to a wide range of cutaneous and mucosal lesions. However, the HPV types most...
7.
Peretti A, Geoghegan E, Pastrana D, Smola S, Feld P, Sauter M, et al.
Cell Host Microbe
. 2018 May;
23(5):628-635.e7.
PMID: 29746834
BK polyomavirus (BKV) frequently causes nephropathy (BKVN) in kidney transplant recipients (KTRs). BKV has also been implicated in the etiology of bladder and kidney cancers. We characterized BKV variants from...
8.
Lu Y, Zheng Z, Robbins P, Tran E, Prickett T, Gartner J, et al.
Mol Ther
. 2017 Nov;
26(2):379-389.
PMID: 29174843
The adoptive transfer of neoantigen-reactive tumor-infiltrating lymphocytes (TILs) can result in tumor regression in patients with metastatic cancer. To improve the efficacy of adoptive T cell therapy targeting these tumor-specific...
9.
Xiao H, Wang F, Wisniewski J, Shaytan A, Ghirlando R, FitzGerald P, et al.
Genes Dev
. 2017 Oct;
31(19):1958-1972.
PMID: 29074736
Histone CENP-A-containing nucleosomes play an important role in nucleating kinetochores at centromeres for chromosome segregation. However, the molecular mechanisms by which CENP-A nucleosomes engage with kinetochore proteins are not well...
10.
He X, Tillo D, Vierstra J, Syed K, Deng C, Ray G, et al.
Genome Biol Evol
. 2015 Oct;
7(11):3155-69.
PMID: 26507798
In mammals, the cytosine in CG dinucleotides is typically methylated producing 5-methylcytosine (5mC), a chemically less stable form of cytosine that can spontaneously deaminate to thymidine resulting in a T•G...