Peter Brouckaert
Overview
Explore the profile of Peter Brouckaert including associated specialties, affiliations and a list of published articles.
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84
Citations
1446
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Recent Articles
1.
Alexander S, Fabbro D, Kelly E, Mathie A, Peters J, Veale E, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S241-S288.
PMID: 38123155
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
2.
Wijnands K, Meesters D, Vandendriessche B, Briede J, van Eijk H, Brouckaert P, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769369
Competition for the amino acid arginine by endothelial nitric-oxide synthase (NOS3) and (pro-)inflammatory NO-synthase (NOS2) during endotoxemia appears essential in the derangement of the microcirculatory flow. This study investigated the...
3.
Alexander S, Fabbro D, Kelly E, Mathie A, Peters J, Veale E, et al.
Br J Pharmacol
. 2021 Sep;
178 Suppl 1:S264-S312.
PMID: 34529829
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
4.
Huyghe L, Van Parys A, Cauwels A, Van Lint S, De Munter S, Bultinck J, et al.
EMBO Mol Med
. 2020 Jan;
12(2):e11223.
PMID: 31912630
Systemic toxicities have severely limited the clinical application of tumor necrosis factor (TNF) as an anticancer agent. Activity-on-Target cytokines (AcTakines) are a novel class of immunocytokines with improved therapeutic index....
5.
Bibli S, Papapetropoulos A, Iliodromitis E, Daiber A, Randriamboavonjy V, Steven S, et al.
Cardiovasc Res
. 2018 Aug;
115(3):625-636.
PMID: 30165375
Aims: Nitroglycerine (NTG) given prior to an ischaemic insult exerts cardioprotective effects. However, whether administration of an acute low dose of NTG in a clinically relevant manner following an ischaemic...
6.
Crassous P, Shu P, Huang C, Gordan R, Brouckaert P, Lampe P, et al.
J Am Heart Assoc
. 2017 Dec;
6(12).
PMID: 29269353
Background: Guanylyl cyclase, a heme-containing α1β1 heterodimer (GC1), produces cGMP in response to Nitric oxide (NO) stimulation. The NO-GC1-cGMP pathway negatively regulates cardiomyocyte contractility and protects against cardiac hypertrophy-related remodeling....
7.
Muenster S, Lieb W, Fabry G, Allen K, Kamat S, Guy A, et al.
Invest Ophthalmol Vis Sci
. 2017 Oct;
58(11):4826-4835.
PMID: 28973329
Purpose: While nitric oxide (NO) donors are emerging as treatments for glaucoma, the mechanism by which NO lowers intraocular pressure (IOP) is unclear. NO activates the enzyme guanylyl cyclase (GC)...
8.
Nagasaka Y, Wepler M, Thoonen R, Sips P, Allen K, Graw J, et al.
BMC Anesthesiol
. 2017 Jun;
17(1):76.
PMID: 28615047
Background: Volatile anesthetics increase levels of the neurotransmitter nitric oxide (NO) and the secondary messenger molecule cyclic guanosine monophosphate (cGMP) in the brain. NO activates the enzyme guanylyl cyclase (GC)...
9.
Bibli S, Zhou Z, Zukunft S, Fisslthaler B, Andreadou I, Szabo C, et al.
Cardiovasc Res
. 2017 Apr;
113(8):926-937.
PMID: 28444132
Aims: Endothelial nitric oxide (NO) synthase (eNOS) is known to play a cardioprotective protective. However, the molecular mechanisms regulating eNOS activity during ischaemia/reperfusion (I/R) injury are incompletely understood. eNOS is...
10.
Ferulic acid-4-O-sulfate rather than ferulic acid relaxes arteries and lowers blood pressure in mice
Van Rymenant E, Van Camp J, Pauwels B, Boydens C, Vanden Daele L, Beerens K, et al.
J Nutr Biochem
. 2017 Apr;
44:44-51.
PMID: 28391055
Consumption of foods rich in ferulic acid (FA) such as wholegrain cereals, or FA precursors such as chlorogenic acids in coffee, is inversely correlated with risk of cardiovascular disease and...