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Peter Bonelt

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Articles 7
Citations 272
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Recent Articles
1.
Wohner M, Pinter T, Bonelt P, Hagelkruys A, Kostanova-Poliakova D, Stadlmann J, et al.
Front Immunol . 2023 Jan; 13:859598. PMID: 36618345
Antibody secretion by plasma cells provides acute and long-term protection against pathogens. The high secretion potential of plasma cells depends on the unfolded protein response, which is controlled by the...
2.
Hagelkruys A, Wirnsberger G, Stadlmann J, Wohner M, Horrer M, Vilagos B, et al.
J Exp Med . 2020 Sep; 218(1). PMID: 32930709
Jagunal homolog 1 (JAGN1) has been identified as a critical regulator of neutrophil biology in mutant mice and rare-disease patients carrying JAGN1 mutations. Here, we report that Jagn1 deficiency results...
3.
Hill L, Ebert A, Jaritz M, Wutz G, Nagasaka K, Tagoh H, et al.
Nature . 2020 Jul; 584(7819):142-147. PMID: 32612238
Nuclear processes, such as V(D)J recombination, are orchestrated by the three-dimensional organization of chromosomes at multiple levels, including compartments and topologically associated domains (TADs) consisting of chromatin loops. TADs are...
4.
Bonelt P, Wohner M, Minnich M, Tagoh H, Fischer M, Jaritz M, et al.
EMBO J . 2018 Dec; 38(2). PMID: 30498131
The transcription factor Blimp1 is not only an essential regulator of plasma cells, but also a risk factor for the development of autoimmune disease in humans. Here, we demonstrate in...
5.
Minnich M, Tagoh H, Bonelt P, Axelsson E, Fischer M, Cebolla B, et al.
Nat Immunol . 2016 Jan; 17(3):331-43. PMID: 26779602
The transcription factor Blimp-1 is necessary for the generation of plasma cells. Here we studied its functions in plasmablast differentiation by identifying regulated Blimp-1 target genes. Blimp-1 promoted the migration...
6.
Kraus H, Kaiser S, Aumann K, Bonelt P, Salzer U, Vestweber D, et al.
J Immunol . 2014 Jan; 192(3):1044-54. PMID: 24379121
The peripheral B cell compartment is maintained by homeostatic proliferation and through replenishment by bone marrow precursors. Because hematopoietic stem cells cycle at a slow rate, replenishment must involve replication...
7.
Salamon D, Adori M, He M, Bonelt P, Severinson E, Kis L, et al.
Cytokine . 2011 Dec; 57(3):360-71. PMID: 22204827
Type I interferons (IFN) exert multiple effects on both the innate and adaptive immune system in addition to their antiviral and antiproliferative activities. Little is known, however about the direct...