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Peter B Moore

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Articles 52
Citations 2057
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Recent Articles
1.
Moore P
Biophys J . 2024 Jun; 123(18):3010-3023. PMID: 38845199
The elongation phase of protein synthesis is a cyclic, steady-state process. It follows that its directionality is determined by the thermodynamics of the accompanying chemical reactions, which strongly favor elongation....
2.
Rothman D, Moore P, Shulman R
Front Cell Dev Biol . 2023 Jun; 11:1197226. PMID: 37377740
Since Jacob and Monod's discovery of the lac operon ∼1960, the explanations offered for most metabolic adaptations have been genetic. The focus has been on the adaptive changes in gene...
3.
Moore P, Hendrickson W, Henderson R, Brunger A
Science . 2022 Feb; 375(6580):507. PMID: 35113705
No abstract available.
4.
Wang J, Natchiar S, Moore P, Klaholz B
Acta Crystallogr D Struct Biol . 2021 Apr; 77(Pt 4):534-539. PMID: 33825713
Cryo electron microscopy (cryo-EM) can produce maps of macromolecules that have resolutions that are sufficiently high that structural details such as chemical modifications, water molecules and bound metal ions can...
5.
Moore P
J Biol Chem . 2021 Mar; 296:100561. PMID: 33744288
This essay, which was written to commemorate the 50th anniversary of the Protein Data Bank, opens with some comments about the intentions of the scientists who pressed for its establishment...
6.
Moore P, Petrov A, Westhof E, Zirbel C
RNA . 2021 Jan; PMID: 33452229
None.
7.
Moore P
Biochemistry . 2019 Jan; 58(6):431-432. PMID: 30648380
No abstract available.
8.
Wang J, Liu Z, Crabtree R, Frank J, Moore P
Protein Sci . 2018 Sep; 27(12):2051-2061. PMID: 30242932
It has long been known that proteins are damaged when they are exposed to the electron beam in an electron microscope. Here we show that exposure to electrons under cryo-EM...
9.
Wang J, Liu Z, Frank J, Moore P
IUCrJ . 2018 Jul; 5(Pt 4):375-381. PMID: 30002838
Cryo-electron microscopy (cryo-EM) directly images the distribution of electrostatic potential (ESP) within macromolecules, and thus can provide much more information about atomic charge than X-ray crystallography. The electron-scattering length of...
10.
Wang J, Brudvig G, Batista V, Moore P
Protein Sci . 2017 Sep; 26(12):2410-2416. PMID: 28960580
In 2012, Karplus and Diederichs demonstrated that the Pearson correlation coefficient CC is a far better indicator of the quality and resolution of crystallographic data sets than more traditional measures...