Peter A Holmans
Overview
Explore the profile of Peter A Holmans including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
60
Citations
12360
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
2.
Cardno A, Allardyce J, Bakker S, Toulopoulou T, Kravariti E, Picchioni M, et al.
Br J Psychiatry
. 2024 Oct;
226(1):16-23.
PMID: 39474930
Background: Positive, negative and disorganised psychotic symptom dimensions are associated with clinical and developmental variables, but differing definitions complicate interpretation. Additionally, some variables have had little investigation. Aims: To investigate...
3.
Tume C, Chick S, Holmans P, Rees E, ODonovan M, Cameron D, et al.
Biol Psychiatry Glob Open Sci
. 2024 Aug;
4(5):100345.
PMID: 39099730
Background: The prefrontal cortex (PFC) has been strongly implicated in the pathophysiology of schizophrenia. Here, we combined high-resolution single-nuclei RNA sequencing data from the human PFC with large-scale genomic data...
4.
Tsang R, Stow D, Kwong A, Donnelly N, Fraser H, Barroso I, et al.
medRxiv
. 2024 Jul;
PMID: 39040209
Studies of longitudinal trends of depressive symptoms in young people could provide insight into aetiologic mechanism, heterogeneity and origin of common cardiometabolic comorbidities for depression. Depression is associated with immunological...
5.
Allardyce J, Cardno A, Gordon-Smith K, Jones L, Di Florio A, Walters J, et al.
Lancet Psychiatry
. 2023 Jul;
10(8):623-631.
PMID: 37437579
Background: Current definitions and clinical heterogeneity in bipolar disorder are major concerns as they obstruct aetiological research and impede drug development. Therefore, stratification of bipolar disorder is a high priority....
6.
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen I, et al.
Nat Commun
. 2023 Feb;
14(1):716.
PMID: 36759603
No abstract available.
7.
Clifton N, Schulmann A, Holmans P, ODonovan M, Vawter M
Am J Med Genet B Neuropsychiatr Genet
. 2023 Jan;
192(5-6):85-92.
PMID: 36652379
Large numbers of genetic loci have been identified that are known to contain common risk alleles for schizophrenia, but linking associated alleles to specific risk genes remains challenging. Given that...
8.
Richards A, Cardno A, Harold G, Craddock N, Di Florio A, Jones L, et al.
JAMA Psychiatry
. 2022 Aug;
79(10):1032-1039.
PMID: 36044200
Importance: Understanding the origins of clinical heterogeneity in bipolar disorder (BD) will inform new approaches to stratification and studies of underlying mechanisms. Objective: To identify components of genetic liability that...
9.
Clifton N, Bosworth M, Haan N, Rees E, Holmans P, Wilkinson L, et al.
Hum Mol Genet
. 2022 May;
31(18):3095-3106.
PMID: 35531971
Large-scale genomic studies of schizophrenia implicate genes involved in the epigenetic regulation of transcription by histone methylation and genes encoding components of the synapse. However, the interactions between these pathways...
10.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature
. 2022 Apr;
604(7906):502-508.
PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...