Pepper Dawes
Overview
Explore the profile of Pepper Dawes including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
15
Followers
0
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Recent Articles
1.
Sundstrom J, Vanderleeden E, Barton N, Redick S, Dawes P, Murray L, et al.
Cells
. 2024 Dec;
13(23).
PMID: 39682726
Viral infections leading to inflammation have been implicated in several common diseases, such as Alzheimer's disease (AD) and type 1 diabetes (T1D). Of note, herpes simplex virus 1 (HSV-1) has...
2.
Funes S, Jung J, Gadd D, Mosqueda M, Zhong J, Shankaracharya , et al.
Nat Commun
. 2024 Mar;
15(1):2497.
PMID: 38509062
Microglia play a pivotal role in neurodegenerative disease pathogenesis, but the mechanisms underlying microglia dysfunction and toxicity remain to be elucidated. To investigate the effect of neurodegenerative disease-linked genes on...
3.
Smullen M, Olson M, Reichert J, Dawes P, Murray L, Baer C, et al.
Cell Rep Methods
. 2023 Sep;
3(9):100570.
PMID: 37751688
Reprogramming somatic cells into pluripotent stem cells (iPSCs) enables the study of systems in vitro. To increase the throughput of reprogramming, we present induction of pluripotency from pooled cells (iPPC)-an...
4.
Funes S, Gadd D, Mosqueda M, Zhong J, Jung J, Shankaracharya , et al.
bioRxiv
. 2023 Jul;
PMID: 37398081
Microglia play a pivotal role in neurodegenerative disease pathogenesis, but the mechanisms underlying microglia dysfunction and toxicity remain to be fully elucidated. To investigate the effect of neurodegenerative disease-linked genes...
5.
Smullen M, Olson M, Murray L, Suresh M, Yan G, Dawes P, et al.
Sci Rep
. 2023 Jun;
13(1):10405.
PMID: 37369829
Mitochondrial (MT) dysfunction has been associated with several neurodegenerative diseases including Alzheimer's disease (AD). While MT-copy number differences have been implicated in AD, the effect of MT heteroplasmy on AD...
6.
Murray L, Olson M, Barton N, Dawes P, Chan Y, Lim E
Methods Mol Biol
. 2023 Jun;
2683:193-199.
PMID: 37300776
Recent technological developments have led to widespread applications of large-scale transcriptomics-based sequencing methods to identify genotype-to-cell type associations. Here we describe a fluorescence-activated cell sorting (FACS)-based sequencing method to utilize...
7.
Dawes P, Murray L, Olson M, Barton N, Smullen M, Suresh M, et al.
Hum Genet
. 2023 Mar;
142(8):1281-1291.
PMID: 36877372
Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged in the identification of critical cell types perturbed by genetic risk variants...
8.
Lim E, Chan Y, Dawes P, Guo X, Erdin S, Tai D, et al.
Nat Commun
. 2022 Jun;
13(1):3243.
PMID: 35688811
Cerebral organoids can be used to gain insights into cell type specific processes perturbed by genetic variants associated with neuropsychiatric disorders. However, robust and scalable phenotyping of organoids remains challenging....