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Nathaniel J Barton

Explore the profile of Nathaniel J Barton including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Readhead B, Mastroeni D, Wang Q, Sierra M, de Avila C, Jimoh T, et al.
Alzheimers Dement . 2024 Dec; 21(1):e14401. PMID: 39698934
Introduction: While there may be microbial contributions to Alzheimer's disease (AD), findings have been inconclusive. We recently reported an AD-associated CD83(+) microglia subtype associated with increased immunoglobulin G4 (IgG4) in...
2.
Sundstrom J, Vanderleeden E, Barton N, Redick S, Dawes P, Murray L, et al.
Cells . 2024 Dec; 13(23). PMID: 39682726
Viral infections leading to inflammation have been implicated in several common diseases, such as Alzheimer's disease (AD) and type 1 diabetes (T1D). Of note, herpes simplex virus 1 (HSV-1) has...
3.
Smullen M, Olson M, Murray L, Suresh M, Yan G, Dawes P, et al.
Sci Rep . 2023 Jun; 13(1):10405. PMID: 37369829
Mitochondrial (MT) dysfunction has been associated with several neurodegenerative diseases including Alzheimer's disease (AD). While MT-copy number differences have been implicated in AD, the effect of MT heteroplasmy on AD...
4.
Dawes P, Murray L, Olson M, Barton N, Smullen M, Suresh M, et al.
Hum Genet . 2023 Mar; 142(8):1281-1291. PMID: 36877372
Cerebral organoids are comprised of diverse cell types found in the developing human brain, and can be leveraged in the identification of critical cell types perturbed by genetic risk variants...
5.
Yates J, Russell R, Barton N, Yost H, Hill J
Nucleic Acids Res . 2021 Sep; 49(22):e131. PMID: 34554233
CRISPR-Cas9 sgRNA libraries have transformed functional genetic screening and have enabled several innovative methods that rely on simultaneously targeting numerous genetic loci. Such libraries could be used in a vast...