Pengchi Deng
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Explore the profile of Pengchi Deng including associated specialties, affiliations and a list of published articles.
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60
Citations
654
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Recent Articles
1.
Liu Z, Zhang C, Li S, Zhou Y, Lan F, Zhao X, et al.
Angew Chem Int Ed Engl
. 2025 Feb;
:e202501936.
PMID: 39972240
The advancement of ring-strain preloaded dipolaro-/dienophiles plays a crucial role in bioorthogonal chemistry, enabling multiple high-precision conjugations toward biomolecules simultaneously. However, durability of these ring-strain preloaded reagents in vivo is...
2.
Jie H, Wei J, Li Z, Yi M, Qian X, Li Y, et al.
Cancer Metab
. 2025 Feb;
13(1):10.
PMID: 39948566
Serine metabolism provides important metabolic intermediates that support the rapid proliferation of tumor cells. However, the role of serine metabolism in esophageal squamous cell carcinoma (ESCC) and the underlying mechanism...
3.
Pu X, Fu Z, Yang Y, Wu D, Deng P, Lan J
J Org Chem
. 2024 Sep;
89(18):13110-13116.
PMID: 39259937
We herein disclose a highly efficient one-pot synthetic strategy for dihydrobenzo[]fluorenes via cascade rhodium(III)-catalyzed -C-H activation/annulation of thiobenzamides with aryl ethynyl ketones and subsequently copper(II)-promoted intramolecular C-H/C-H cross-coupling reactions. Mechanistic...
4.
Gao J, Xiong Q, Wu X, Deng J, Zhang X, Zhao X, et al.
Commun Chem
. 2023 Jan;
3(1):29.
PMID: 36703431
Ultra-fast and selective covalent-bond forming reactions with spatiotemporal controllability are foundational for developing a bioorthogonal approach with high manipulability. However, it is challenging to exploit a reporter functional group to...
5.
Liu H, Wang Y, Han Y, Yang G, Wang L, Peng J, et al.
Asia Pac J Clin Nutr
. 2022 Sep;
31(3):526-533.
PMID: 36173224
Background And Objectives: To optimize the pretreatment method of colorectal cancer tissue samples for metabolomics research based on solid-phase nuclear magnetic resonance (NMR). Methods And Study Design: The mucosal tissues...
6.
Shen X, Zhang C, Lan F, Su Z, Zheng Y, Zheng T, et al.
Angew Chem Int Ed Engl
. 2022 Aug;
61(41):e202209441.
PMID: 36002933
Tetra-ortho-substituted, heteroaryl and cyclic azobenzenes have emerged as three key strategies on morphology design of photoswitch to diversify controllability. Cyclic azobenzene is of particular utilization in photo-energy conversion due to...
7.
Zeng J, Peng J, Jiang H, Deng P, Li K, Long D, et al.
PLoS One
. 2022 Aug;
17(8):e0266730.
PMID: 35972924
Objective: To prospectively establish an early diagnosis model of acute colon cancerous bowel obstruction by applying nuclear magnetic resonance hydrogen spectroscopy(1H NMR) technology based metabolomics methods, combined with machine learning....
8.
Zhai Y, Deng P, Wang X, Zhang C, Gan R, Gan N, et al.
RSC Adv
. 2022 May;
8(55):31555-31563.
PMID: 35548207
The interaction mechanism between olaparib (OLA) and human serum albumin (HSA) has been investigated using experimental and computational techniques. An NMR relaxation approach based on the analysis of proton selective...
9.
Zheng Y, Zhou Y, Zhang Y, Deng P, Zhao X, Jiang S, et al.
Chem Asian J
. 2021 Dec;
17(2):e202101239.
PMID: 34851039
Cyclic azodicarbonyl derivatives, particularly 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD), commonly serve as arenophile, dienophile, enophile and electrophile. Perplexed by its instability in aqueous environment, there are few studies focused on the transient intermediate...
10.
Liu C, Wang L, Liu X, Tan Y, Tao L, Xiao Y, et al.
Theranostics
. 2021 Jan;
11(6):2966-2986.
PMID: 33456583
Serine hydroxymethyltransferase 2 (SHMT2) plays a critical role in serine-glycine metabolism to drive cancer cell proliferation. However, the nonmetabolic function of SHMT2 in tumorigenesis, especially in human colorectal cancer (CRC)...