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Pei-Jung Lu

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Articles 127
Citations 2770
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Recent Articles
11.
Ho C, Lin Y, Chen H, Ho W, Sun G, Hsiao M, et al.
J Neuroinflammation . 2020 Jun; 17(1):185. PMID: 32532282
Background: Inflammation is a common pathophysiological trait found in both hypertension and cardiac vascular disease. Recent evidence indicates that fractalkine (FKN) and its receptor CX3CR1 have been linked to inflammatory...
12.
Ko H, Chiou S, Wong Y, Wang Y, Lai Y, Chou C, et al.
J Clin Med . 2019 Oct; 8(10). PMID: 31640277
Based on the protein kinase A (PKA)/GSK3β interaction protein (GSKIP)/glycogen synthase kinase 3β (GSK3β) axis, we hypothesized that these might play a role in Tau phosphorylation. Here, we report that...
13.
Lin C, Li H, Liu Y, Kuo P, Wang W, Lin F, et al.
Ther Adv Med Oncol . 2019 Oct; 11:1758835919875324. PMID: 31632466
Background: Esophageal squamous cell carcinoma (ESCC) is the major type of esophageal cancer in Asia and demonstrates poor survival rates following a therapeutic regimen. Methods: Cancer stem cells (CSCs) are...
14.
Chang Y, Chiou J, Yang Y, Su C, Lin Y, Yang C, et al.
Cancer Res . 2019 Jul; 79(18):4754-4766. PMID: 31358528
Cancer metabolic reprogramming promotes tumorigenesis and metastasis; however, the underlying molecular mechanisms are still being uncovered. In this study, we show that the glycolytic enzyme aldolase A (ALDOA) is a...
15.
Wang P, Chou C, Lin C, Yao Y, Cheng H, Li H, et al.
Oncogene . 2018 May; 37(34):4662-4678. PMID: 29755127
Triple-negative breast cancer (TNBC) patients usually lead to poor prognosis and survival because of metastasis. The major sites for TNBC metastasis include the lungs, brain, liver, and bone. Long non-coding...
16.
Li H, Liang J, Kuo Y, Lee H, Calkins M, Chang H, et al.
Breast Cancer Res . 2017 Dec; 19(1):133. PMID: 29258605
Background: Triple negative breast cancer (TNBC) lacks both early detection biomarkers and viable targeted therapeutics. Moreover, chemotherapy only produces 20-30% pathologic complete response. Because miRNAs are frequently dysregulated in breast...
17.
Cheng P, Lin Y, Ho W, Lu P, Chen H, Lai C, et al.
Free Radic Biol Med . 2017 Jul; 112:298-307. PMID: 28754499
Type 2 diabetes are at a high risk of complications related to hypertension, and reports have indicated that insulin levels may be associated with blood pressure (BP). Fructose intake has...
18.
Chen H, Cheng P, Ho W, Lu P, Lai C, Tseng Y, et al.
Sci Rep . 2016 Dec; 6:38447. PMID: 27917928
Hypertensive rats with chronic kidney disease (CKD) exhibit enhanced gamma-aminobutyric acid (GABA) receptor function and regulation within the nucleus tractus solitarii (NTS). For CKD with hypertension, renal denervation (RD) interrupts...
19.
Chang W, Lai W, Kuo I, Lin C, Lu P, Sheu B, et al.
J Gastroenterol . 2016 Sep; 52(6):705-714. PMID: 27671002
Background: Prognosis of esophageal squamous cell carcinoma (ESCC) patients remains poor, and the chemoradiotherapy (CRT) applied to ESCC patients often failed. Therefore, development of biomarkers to predict CRT response is...
20.
Tai Y, Tung L, Lin Y, Lu P, Chu P, Wang M, et al.
PLoS One . 2016 Sep; 11(9):e0163617. PMID: 27658202
Growth factor receptor bound protein-7 (Grb7) is a multi-domain adaptor protein that is co-opted by numerous tyrosine kinases involved in various cellular signaling and functions. The molecular mechanisms underlying the...