Peggy Wan
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Explore the profile of Peggy Wan including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Wang A, Van Blarigan E, Cheng I, Chan J, Wan P, Park S, et al.
JAMA Netw Open
. 2025 Feb;
8(2):e2460785.
PMID: 40009382
Importance: Prostate cancer (PCa) remains a leading cause of cancer-related death among men in the US. Objective: To evaluate the association of healthy lifestyle and dietary behaviors with survival after...
2.
Polygenic Risk Score Modifies Prostate Cancer Risk of Pathogenic Variants in Men of African Ancestry
Hughley R, Matejcic M, Song Z, Sheng X, Wan P, Xia L, et al.
Cancer Res Commun
. 2023 Nov;
3(12):2544-2550.
PMID: 38014910
Significance: These findings highlight the importance of considering rare and common variants to comprehensively assess prostate cancer risk in men of African ancestry.
3.
Wang A, Shen J, Rodriguez A, Saunders E, Chen F, Janivara R, et al.
Nat Genet
. 2023 Nov;
55(12):2065-2074.
PMID: 37945903
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry...
4.
Darst B, Saunders E, Dadaev T, Sheng X, Wan P, Pooler L, et al.
JAMA Oncol
. 2023 Sep;
9(11):1514-1524.
PMID: 37733366
Importance: Germline gene panel testing is recommended for men with advanced prostate cancer (PCa) or a family history of cancer. While evidence is limited for some genes currently included in...
5.
Wang A, Wan P, Hebert J, Le Marchand L, Wilkens L, Haiman C
Br J Cancer
. 2023 Jul;
129(6):974-981.
PMID: 37488447
Background: Previous studies investigating relationship between atopic allergic conditions (AACs)-a highly reactive immune state-and prostate cancer (PCa) risk were inconclusive, and few have studied diverse racial/ethnic populations. Methods: We analysed...
6.
Darst B, Shen J, Madduri R, Rodriguez A, Xiao Y, Sheng X, et al.
Am J Hum Genet
. 2023 Jun;
110(7):1200-1206.
PMID: 37311464
Genome-wide polygenic risk scores (GW-PRSs) have been reported to have better predictive ability than PRSs based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several...
7.
Darst B, Shen J, Madduri R, Rodriguez A, Xiao Y, Sheng X, et al.
medRxiv
. 2023 Jun;
PMID: 37292833
Genome-wide polygenic risk scores (GW-PRS) have been reported to have better predictive ability than PRS based on genome-wide significance thresholds across numerous traits. We compared the predictive ability of several...
8.
Chen F, Madduri R, Rodriguez A, Darst B, Chou A, Sheng X, et al.
Eur Urol
. 2023 Mar;
84(1):13-21.
PMID: 36872133
Background: Genetic factors play an important role in prostate cancer (PCa) susceptibility. Objective: To discover common genetic variants contributing to the risk of PCa in men of African ancestry. Design,...
9.
Wang A, Xu Y, Yu Y, Nead K, Kim T, Xu K, et al.
Hum Mol Genet
. 2022 Aug;
32(3):489-495.
PMID: 36018819
Little is known regarding the potential relationship between clonal hematopoiesis (CH) of indeterminate potential (CHIP), which is the expansion of hematopoietic stem cells with somatic mutations, and risk of prostate...
10.
Chen F, Park S, Wilkens L, Wan P, Hart S, Hu C, et al.
Cancer Res
. 2022 Jul;
82(18):3201-3208.
PMID: 35834270
Significance: This multiethnic study links germline pathogenic variants in BRCA1, BRCA2, and ERCC2 to the development of second primary cancer in breast cancer survivors, providing biological insights and biomarkers to...