Stephen J Chanock
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Explore the profile of Stephen J Chanock including associated specialties, affiliations and a list of published articles.
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844
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51398
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Recent Articles
1.
Ugalde-Morales E, Wilf R, Pluta J, Ploner A, Fan M, Damra M, et al.
Am J Hum Genet
. 2025 Feb;
112(3):630-643.
PMID: 39999848
Transcriptome-wide association studies (TWASs) have the potential to identify susceptibility genes associated with testicular germ cell tumors (TGCTs). We conducted a comprehensive TGCT TWAS by integrating genome-wide association study (GWAS)...
2.
Florez-Vargas O, Ho M, Hogshead M, Papenberg B, Lee C, Forsythe K, et al.
Nat Commun
. 2025 Feb;
16(1):1676.
PMID: 39956830
The chromosome 5p15.33 region, which encodes telomerase reverse transcriptase (TERT), harbors multiple germline variants identified by genome-wide association studies (GWAS) as risk for some cancers but protective for others. Here,...
3.
Hoffmann T, Graff R, Madduri R, Rodriguez A, Cario C, Feng K, et al.
Nat Genet
. 2025 Feb;
57(2):334-344.
PMID: 39930085
We conducted a multiancestry genome-wide association study of prostate-specific antigen (PSA) levels in 296,754 men (211,342 European ancestry, 58,236 African ancestry, 23,546 Hispanic/Latino and 3,630 Asian ancestry; 96.5% of participants...
4.
Kachuri L, Hoffmann T, Jiang Y, Berndt S, Shelley J, Schaffer K, et al.
Nat Med
. 2025 Feb;
31(2):697.
PMID: 39901049
No abstract available.
5.
Tanu T, Cox A, Karlow J, Sharma P, He X, Wu C, et al.
bioRxiv
. 2025 Jan;
PMID: 39868094
Endogenous retroviral (ERV) RNA is highly expressed in cancer, although the molecular causes and consequences remain unknown. We found that ZC3H18 (Z18), a component of multiple nuclear RNA surveillance complexes,...
6.
Florez-Vargas O, Ho M, Hogshead M, Lee C, Papenberg B, Forsythe K, et al.
medRxiv
. 2025 Jan;
PMID: 39802763
The chromosome 5p15.33 region, which encodes telomerase reverse transcriptase (TERT), harbors multiple germline variants identified by genome-wide association studies (GWAS) as risk for some cancers but protective for others. We...
7.
Lee O, Karyadi D, Hartley S, Zhou W, Zhou W, Machiela M, et al.
Eur Thyroid J
. 2025 Jan;
14(1).
PMID: 39773491
Deletion of the long q arm of chromosome 22 (22qDEL) is the most frequently identified recurrent somatic copy number alteration observed in papillary thyroid carcinoma (PTC). Since its role in...
8.
Masiuk S, Chepurny M, Buderatska V, Ivanova O, Boiko Z, Zhadan N, et al.
Radiat Environ Biophys
. 2024 Dec;
PMID: 39699684
Increased thyroid cancer incidence has been one of the principal adverse health effects of the Chornobyl (Chernobyl) nuclear power plant accident. Accurate dose estimation is critical for assessing the radiation...
9.
Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat S, Kentistou K, et al.
Nature
. 2024 Dec;
636(8043):E7.
PMID: 39627447
No abstract available.
10.
Blechter B, Hsiung C, Wang X, Zhang H, Seow W, Shi J, et al.
J Thorac Oncol
. 2024 Nov;
PMID: 39581378
We assessed the association between a genome-wide polygenic risk score (PRS) developed for lung adenocarcinoma (LUAD) risk and mutation on the EGFR gene in 998 East Asian never-smoking female LUAD...