Payam E Farahani
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Explore the profile of Payam E Farahani including associated specialties, affiliations and a list of published articles.
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7
Citations
65
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Recent Articles
1.
Suh K, Thornton R, Nguyen L, Farahani P, Cohen D, Toettcher J
Cell Syst
. 2025 Mar;
:101203.
PMID: 40037348
Receptor tyrosine kinases (RTKs) play key roles in coordinating cell movement at both single-cell and tissue scales. The recent development of optogenetic tools for controlling RTKs and their downstream signaling...
2.
Ho E, Kim-Yip R, Simpkins A, Farahani P, Oatman H, Posfai E, et al.
bioRxiv
. 2025 Jan;
PMID: 39829924
A lack of tools for detecting receptor activity has limited our ability to fully explore receptor-level control of developmental patterning. Here, we extend a new class of biosensors for receptor...
3.
Suh K, Thornton R, Farahani P, Cohen D, Toettcher J
bioRxiv
. 2024 Jun;
PMID: 38853934
Receptor tyrosine kinases (RTKs) are thought to play key roles in coordinating cell movement at single-cell and tissue scales. The recent development of optogenetic tools for controlling RTKs and their...
4.
Farahani P, Yang X, Mesev E, Fomby K, Brumbaugh-Reed E, Bashor C, et al.
Elife
. 2023 May;
12.
PMID: 37212240
Receptor tyrosine kinases (RTKs) are major signaling hubs in metazoans, playing crucial roles in cell proliferation, migration, and differentiation. However, few tools are available to measure the activity of a...
5.
Farahani P, Lemke S, Dine E, Uribe G, Toettcher J, Nelson C
Cell Rep
. 2021 Dec;
37(13):110181.
PMID: 34965432
The EGFR/Erk pathway is triggered by extracellular ligand stimulation, leading to stimulus-dependent dynamics of pathway activity. Although mechanical properties of the microenvironment also affect Erk activity, their effects on Erk...
6.
Farahani P, Nelson C
Curr Opin Genet Dev
. 2021 Dec;
72:61-68.
PMID: 34864332
Epithelial morphogenesis is guided by mechanical forces and biochemical signals that vary spatiotemporally. As many morphogenetic events are driven by rapid cellular processes, understanding morphogenesis requires monitoring development in real...
7.
Farahani P, Reed E, Underhill E, Aoki K, Toettcher J
Annu Rev Biomed Eng
. 2021 Mar;
23:61-87.
PMID: 33722063
Cells receive enormous amounts of information from their environment. How they act on this information-by migrating, expressing genes, or relaying signals to other cells-comprises much of the regulatory and self-organizational...
8.
Farahani P, Adelmund S, Shadish J, DeForest C
J Mater Chem B
. 2020 Apr;
5(23):4435-4442.
PMID: 32263971
Click chemistry has proved a valuable tool in biocompatible hydrogel formation for 3D cell culture, owing to its bioorthogonal nature and high efficiency under physiological conditions. While traditional click reactions...
9.
Adelmund S, Ruskowitz E, Farahani P, Wolfe J, DeForest C
ACS Chem Biol
. 2018 Feb;
13(3):573-577.
PMID: 29419281
This work introduces light-activated bioorthogonal noncanonical amino acid tagging (laBONCAT) as a method to selectively label, isolate, and identify proteins newly synthesized at user-defined regions in tissue culture. By photocaging...