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Pavlos Anastasiadis

Explore the profile of Pavlos Anastasiadis including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 210
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Recent Articles
1.
Blanchard A, Maximova A, Phillips-Jones T, Bruce M, Anastasiadis P, Dionisos C, et al.
Dev Cell . 2024 Dec; PMID: 39662467
Brain development is a non-linear process of regionally specific epochs occurring during windows of sensitivity to endogenous and exogenous stimuli. We have identified an epoch in the neonatal rat brain...
2.
Chen H, Anastasiadis P, Woodworth G
Magn Reson Imaging Clin N Am . 2024 Sep; 32(4):673-679. PMID: 39322356
Malignant gliomas (MGs) are the most common primary brain tumors in adults. Despite recent advances in understanding the biology and potential therapeutic vulnerabilities of MGs, treatment options remain limited as...
3.
Nikas S, Zonitsa S, Anastasiadis P, Veniadou K, Roumelioti S, Mitsas A, et al.
Cureus . 2024 Jul; 16(6):e61968. PMID: 38978945
We present a unique case of a retroperitoneal tumefactive fibroinflammatory lesion related to IgG4-sclerosing disease; it is a rare manifestation of the IgG4-related disease, which usually causes diffuse fibrosis when...
4.
Seas A, Malla A, Sharifai N, Winkles J, Woodworth G, Anastasiadis P
Biomedicines . 2024 Jun; 12(6). PMID: 38927437
Infiltrating gliomas are challenging to treat, as the blood-brain barrier significantly impedes the success of therapeutic interventions. While some clinical trials for high-grade gliomas have shown promise, patient outcomes remain...
5.
Zierden H, Marx-Rattner R, Rock K, Montgomery K, Anastasiadis P, Folts L, et al.
Sci Rep . 2023 Mar; 13(1):4568. PMID: 36941297
Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and fetal health. The placenta facilitates critical communication between maternal and fetal compartments, in part, through the production...
6.
Carney C, Kapur A, Anastasiadis P, Ritzel R, Chen C, Woodworth G, et al.
Mol Pharm . 2022 Nov; 20(1):314-330. PMID: 36374573
Triple-negative breast cancer (TNBC) patients with brain metastasis (BM) face dismal prognosis due to the limited therapeutic efficacy of the currently available treatment options. We previously demonstrated that paclitaxel-loaded PLGA-PEG...
7.
Pandey N, Anastasiadis P, Carney C, Kanvinde P, Woodworth G, Winkles J, et al.
Adv Drug Deliv Rev . 2022 Jul; 188:114415. PMID: 35787387
Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to the brain-invading tumor cells...
8.
Pang S, Kapur A, Zhou K, Anastasiadis P, Ballirano N, Kim A, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol . 2022 Jun; 14(5):e1826. PMID: 35735205
Laser interstitial thermal therapy (LITT) guided by magnetic resonance imaging (MRI) is a new treatment option for patients with brain and non-central nervous system (non-CNS) tumors. MRI guidance allows for...
9.
Alomari S, Kedda J, Malla A, Pacis V, Anastasiadis P, Xu S, et al.
J Vis Exp . 2022 May; (183). PMID: 35604202
The present protocol describes a standardized paradigm for rodent brain tumor resection and tissue preservation. In clinical practice, maximal tumor resection is the standard-of-care treatment for most brain tumors. However,...
10.
Anastasiadis P, Gandhi D, Guo Y, Ahmed A, Bentzen S, Arvanitis C, et al.
Proc Natl Acad Sci U S A . 2021 Sep; 118(37). PMID: 34504017
Pharmacological treatment of gliomas and other brain-infiltrating tumors remains challenging due to limited delivery of most therapeutics across the blood-brain barrier (BBB). Transcranial MRI-guided focused ultrasound (FUS), an emerging technology...