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» Authors » Pavel S Chelushkin

Pavel S Chelushkin

Explore the profile of Pavel S Chelushkin including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 82
Followers 0
Related Specialties
Chemistry
Biochemistry
Pharmacology
Top 10 Co-Authors
Sergey P Tunik
Anastasia I Solomatina
Pi-Tai Chou
Evgeny A Lysenko
Alexander V Kabanov
Igor O Koshevoy
Shih-Hao Su
Alexei S Melnikov
Tatiana K Bronich
Natalia V Nukolova
Published In
J Phys Chem B
RSC Adv
Langmuir
Bioconjug Chem
Mol Pharm
Affiliations
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Recent Articles
1.
The Dual Luminescence Lifetime pH/Oxygen Sensor: Evaluation of Applicability for Intravital Analysis of 2D- and 3D-Cultivated Human Endometrial Mesenchymal Stromal Cells
Litvinov I, Belyaeva T, Salova A, Aksenov N, Chelushkin P, Solomatina A, et al.
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958592
The oxygenation of cells and tissues and acidification of the cellular endolysosomal system are among the major factors that ensure normal functioning of an organism and are violated in various...
2.
Amphiphilic Diblock Copolymers Bearing Poly(Ethylene Glycol) Block: Hydrodynamic Properties in Organic Solvents and Water Micellar Dispersions, Effect of Hydrophobic Block Chemistry on Dispersion Stability and Cytotoxicity
Elistratova A, Gubarev A, Lezov A, Vlasov P, Solomatina A, Liao Y, et al.
Polymers (Basel) . 2022 Oct; 14(20). PMID: 36297939
Despite the fact that amphiphilic block copolymers have been studied in detail by various methods both in common solvents and aqueous dispersions, their hydrodynamic description is still incomplete. In this...
3.
Aggregation-Induced Ignition of Near-Infrared Phosphorescence of Non-Symmetric [Pt(C^N*N'^C')] Complex in Poly(caprolactone)-based Block Copolymer Micelles: Evaluating the Alternative Design of Near-Infrared Oxygen Biosensors
Zharskaia N, Solomatina A, Liao Y, Galenko E, Khlebnikov A, Chou P, et al.
Biosensors (Basel) . 2022 Sep; 12(9). PMID: 36140080
In the present work, we described the preparation and characterization of the micelles based on amphiphilic poly(ε-caprolactone--ethylene glycol) block copolymer () loaded with non-symmetric [Pt(C^N*N'^C')] complex () (where C^N*N'^C': 6-(phenyl(6-(thiophene-2-yl)pyridin-2-yl)amino)-2-(tyophene-2-yl)nicotinate)....
4.
Water-soluble cyclometalated platinum(ii) and iridium(iii) complexes: synthesis, tuning of the photophysical properties, and and phosphorescence lifetime imaging
Solomatina A, Su S, Lukina M, Dudenkova V, Shcheslavskiy V, Wu C, et al.
RSC Adv . 2022 May; 8(31):17224-17236. PMID: 35539280
This paper presents synthesis and photophysical investigation of cyclometalated water-soluble Pt(ii) and Ir(iii) complexes containing auxiliary sulfonated diphosphine (bis(diphenylphosphino)benzene (dppb), P^P*) ligand. The complexes demonstrate considerable variations in excitation (extending...
5.
Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for and application in luminescent bioimaging
Shakirova J, Sadeghi A, Koblova A, Chelushkin P, Toropainen E, Tavakoli S, et al.
RSC Adv . 2022 May; 10(24):14431-14440. PMID: 35498460
Two iridium [Ir(N^C)(N^N)] complexes with the diimine N^N ligand containing a long polymethylene hydrophobic chain were synthesized and characterized by using NMR and ESI mass-spectrometry: N^N - 2-(1-hexadecyl-1-imidazol-2-yl)pyridine, N^C -...
6.
Combined fluorophore and phosphor conjugation: a new design concept for simultaneous and spatially localized dual lifetime intracellular sensing of oxygen and pH
Solomatina A, Chelushkin P, Su S, Wu C, Chou P, Tunik S
Chem Commun (Camb) . 2021 Dec; 58(3):419-422. PMID: 34897308
In this communication, we propose a new strategy for double-parametric biosensing and present a dual pH/O lifetime sensor based on the covalent conjugation of fluorescein (pH sensor) and an orthometalated...
7.
Phosphorescent NIR emitters for biomedicine: applications, advances and challenges
Chelushkin P, Shakirova J, Kritchenkov I, Baigildin V, Tunik S
Dalton Trans . 2021 Dec; 51(4):1257-1280. PMID: 34878463
Application of NIR (near-infrared) emitting transition metal complexes in biomedicine is a rapidly developing area of research. Emission of this class of compounds in the "optical transparency windows" of biological...
8.
Blood-Brain Barrier Penetrating Luminescent Conjugates Based on Cyclometalated Platinum(II) Complexes
Solomatina A, Slobodina A, Ryabova E, Bolshakova O, Chelushkin P, Sarantseva S, et al.
Bioconjug Chem . 2020 Oct; 31(11):2628-2637. PMID: 33048524
Herein we report on the synthesis, structural characterization and photophysical properties of cyclometalated Pt(II) complexes [Pt(N^C)(PPh(CHCOOH))Cl] (where N^C ligands are 2-phenylpyridine, (2-benzofuran-3-yl)pyridine, and (2-benzo[]tiophen-3-yl)pyridine) and their conjugates with the histidine-containing...
9.
Reactions of Cyclometalated Platinum(II) [Pt(NC)(PR)Cl] Complexes with Imidazole and Imidazole-Containing Biomolecules: Fine-Tuning of Reactivity and Photophysical Properties via Ligand Design
Solomatina A, Chelushkin P, Abakumova T, Zhemkov V, Kim M, Bezprozvanny I, et al.
Inorg Chem . 2018 Oct; 58(1):204-217. PMID: 30376305
This work describes interaction of a family of [Pt(NC)(PR)Cl] complexes with imidazole (Im), possible application of this chemistry for regioselective labeling of proteins through imidazole rings of histidine residues and...
10.
Coordination to Imidazole Ring Switches on Phosphorescence of Platinum Cyclometalated Complexes: The Route to Selective Labeling of Peptides and Proteins via Histidine Residues
Solomatina A, Chelushkin P, Krupenya D, Podkorytov I, Artamonova T, Sizov V, et al.
Bioconjug Chem . 2016 Dec; 28(2):426-437. PMID: 27977146
In this study, we have shown that substitution of chloride ligand for imidazole (Im) ring in the cyclometalated platinum complex Pt(phpy)(PPh)Cl (1; phpy, 2-phenylpyridine; PPh, triphenylphosphine), which is nonemissive in...