Pavan Kumar Kakumani
Overview
Explore the profile of Pavan Kumar Kakumani including associated specialties, affiliations and a list of published articles.
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15
Citations
245
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Recent Articles
1.
Patel M, Jiang Y, Kakumani P
Front Cell Dev Biol
. 2024 Dec;
12:1495035.
PMID: 39717847
PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that bind to the PIWI subclass of the Argonaute protein family and are essential for maintaining germline integrity. Initially discovered in , PIWI...
2.
Hynes C, Kakumani P
Front Mol Biosci
. 2024 Apr;
11:1374843.
PMID: 38567098
MicroRNAs (miRNAs) are small non-coding RNAs that silence gene expression through their interaction with complementary sequences in the 3' untranslated regions (UTR) of target mRNAs. miRNAs undergo a series of...
3.
Kakumani P, Ko Y, Ramakrishna S, Christopher G, Dodgson M, Shrinet J, et al.
Nucleic Acids Res
. 2023 Jul;
51(17):9385-9396.
PMID: 37493604
MicroRNAs are sequentially processed by RNase III enzymes Drosha and Dicer. miR-451 is a highly conserved miRNA in vertebrates which bypasses Dicer processing and instead relies on AGO2 for its...
4.
Kakumani P
Transl Oncol
. 2022 Apr;
21:101434.
PMID: 35477066
MicroRNAs (miRNAs) and RNA-binding proteins (RBPs) are important regulators of mRNA translation and stability in eukaryotes. While miRNAs can only bind their target mRNAs in association with Argonaute proteins (AGOs),...
5.
Kakumani P, Guitart T, Houle F, Harvey L, Goyer B, Germain L, et al.
Oncogene
. 2021 Apr;
40(18):3231-3244.
PMID: 33833398
MicroRNAs and RNA-binding proteins (RBPs) primarily target the 3' UTR of mRNAs to control their translation and stability. However, their co-regulatory effects on specific mRNAs in physiology and disease are...
6.
Kakumani P, Harvey L, Houle F, Guitart T, Gebauer F, Simard M
Life Sci Alliance
. 2020 Mar;
3(4).
PMID: 32161113
In animals, miRNAs are the most prevalent small non-coding RNA molecules controlling posttranscriptional gene regulation. The Argonaute proteins (AGO) mediate miRNA-guided gene silencing by recruiting multiple factors involved in translational...
7.
Kakumani P, Medigeshi G, Kaur I, Malhotra P, Mukherjee S, Bhatnagar R
Gene
. 2016 Apr;
586(1):7-11.
PMID: 27039024
In recent times, RNAi has emerged as an important defence system that regulates replication of pathogens in host cells. Many RNAi related host factors especially the host miRNAs play important...
8.
Kakumani P, Shanmugam R, Kaur I, Malhotra P, Mukherjee S, Bhatnagar R
Biochem Biophys Res Commun
. 2015 Sep;
466(3):481-5.
PMID: 26367179
In RNA silencing, small RNAs produced by dicer mediate target repression guided by RNA induced silencing complex (RISC). To effectively mediate this response, one or more proteins are employed at...
9.
Kakumani P, Shukla R, Todur V, Malhotra P, Mukherjee S, Bhatnagar R
Biol Direct
. 2015 Aug;
10:44.
PMID: 26290335
Spodoptera is an important polyphagous agricultural insect pest in the tropical world. The genomic details are limited to understand the pest biology at molecular level. In the present study, we...
10.
Kakumani P, Rajgokul K, Ponia S, Kaur I, Mahanty S, Medigeshi G, et al.
Biochem J
. 2015 Jul;
471(1):89-99.
PMID: 26221025
RNAi acts as a host immune response against non-self molecules, including viruses. Viruses evolved to neutralize this response by expressing suppressor proteins. In the present study, we investigated dengue virus...