Pauline M W van Kempen
Overview
Explore the profile of Pauline M W van Kempen including associated specialties, affiliations and a list of published articles.
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17
Citations
303
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Recent Articles
1.
van Dam-Kastelein J, Gorter-Houtman N, Donker D, Buwalda J, van Kempen P
Ned Tijdschr Geneeskd
. 2022 Oct;
166.
PMID: 36300468
Acute sore throat is one of the most common problems in general practice. It usually concerns a viral oropharyngeal infection, with good recovery within 10 days. In current guidelines, antibiotics...
2.
Swartz J, Wegner I, Noorlag R, van Kempen P, van Es R, de Bree R, et al.
Head Neck
. 2020 Nov;
43(3):745-756.
PMID: 33155375
Background: Hypoxia is a negative prognostic factor in head and neck squamous cell carcinomas. Under hypoxia, the hypoxia-inducible factor (HIF)-1a transcription factor is overexpressed. We investigated whether there were site...
3.
van Kempen P, Peters H, Thomeer H
Ned Tijdschr Geneeskd
. 2019 Nov;
163.
PMID: 31769631
A 35-year-old woman developed acute swallowing problems caused by a big oral blood blister after eating nuts. The blister ruptured 32 hours later and healed without scarring. 'Angina bullosa haemorrhagica'...
4.
Swartz J, Driessen J, van Kempen P, de Bree R, Janssen L, Pameijer F, et al.
Oral Oncol
. 2018 Jan;
77:9-15.
PMID: 29362130
Objectives: Diffusion weighted imaging (DWI) is a frequently performed MRI sequence in cancer patients. While previous studies have shown the clinical value of the apparent diffusion coefficient (ADC) for response...
5.
Koole K, Clausen M, van Es R, van Kempen P, Melchers L, Koole R, et al.
Mol Diagn Ther
. 2016 Jun;
20(4):363-74.
PMID: 27278367
Introduction: Fibroblast growth factor receptor family member proteins (FGFR1-4) have been identified as promising novel therapeutic targets and prognostic markers in a wide spectrum of solid tumors. The present study...
6.
van Kempen P, Noorlag R, Swartz J, Bovenschen N, Braunius W, Vermeulen J, et al.
Cancer Immunol Immunother
. 2016 Mar;
65(5):575-85.
PMID: 26993499
Objectives: Patients with human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinomas (OPSCCs) have an improved prognosis compared to HPV-negative OPSCCs. Several theories have been proposed to explain this relatively good prognosis....
7.
Koole K, Brunen D, van Kempen P, Noorlag R, de Bree R, Lieftink C, et al.
Clin Cancer Res
. 2016 Mar;
22(15):3884-93.
PMID: 26936917
Purpose: FGFR1 is a promising therapeutic target in multiple types of solid tumors, including head and neck squamous cell carcinoma (HNSCC). FGFR inhibitors have shown great therapeutic value in preclinical...
8.
Koole K, van Kempen P, Swartz J, Peeters T, van Diest P, Koole R, et al.
Cancer Med
. 2015 Dec;
5(2):275-84.
PMID: 26711175
Fibroblast growth factor receptor 3 (FGFR3) is a member of the fibroblast growth factor receptor tyrosine kinase family. It has been identified as a promising therapeutic target in multiple types...
9.
Koole K, van Kempen P, van Bockel L, Smets T, van der Klooster Z, Dutman A, et al.
Pathobiology
. 2015 Nov;
82(6):280-9.
PMID: 26551585
Objective: The aim of this study was to investigate whether fibroblast growth factor receptor 4 (FGFR4) could serve as a potential therapeutic target, prognostic biomarker or biomarker predicting radiotherapy sensitivity...
10.
van Kempen P, Noorlag R, Braunius W, Moelans C, Rifi W, Savola S, et al.
Cancer Med
. 2015 Jul;
4(10):1525-35.
PMID: 26194878
Current conventional treatment modalities in head and neck squamous cell carcinoma (HNSCC) are nonselective and have shown to cause serious side effects. Unraveling the molecular profiles of head and neck...