Paulina Sprezyna
Overview
Explore the profile of Paulina Sprezyna including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
21
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Recent Articles
1.
Kilian C, Ulrich H, Zouboulis V, Sprezyna P, Schreiber J, Landsberger T, et al.
NPJ Syst Biol Appl
. 2024 Jun;
10(1):69.
PMID: 38914538
Single-cell-based methods such as flow cytometry or single-cell mRNA sequencing (scRNA-seq) allow deep molecular and cellular profiling of immunological processes. Despite their high throughput, however, these measurements represent only a...
2.
Hagenstein J, Burkhardt S, Sprezyna P, Tasika E, Tiegs G, Diehl L
J Leukoc Biol
. 2024 Mar;
116(1):177-185.
PMID: 38484149
In chronic inflammation, regulatory immune cells, such as regulatory T cells and myeloid-derived suppressor cells, can develop. Local signals in the inflamed tissue, such as cytokines and eicosanoids, but also...
3.
Geers B, Hagenstein J, Endig J, Ulrich H, Fleig L, Sprezyna P, et al.
Cells
. 2022 Sep;
11(17).
PMID: 36078047
Interleukin-2 is central to the induction and maintenance of both natural (nT) and induced Foxp3-expressing regulatory T cells (iT). Thus, signals that modulate IL-2 availability may, in turn, also influence...
4.
Unrau L, Endig J, Goltz D, Sprezyna P, Ulrich H, Hagenstein J, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769006
Myeloid cells play an essential role in the maintenance of liver homeostasis, as well as the initiation and termination of innate and adaptive immune responses. In chronic hepatic inflammation, the...
5.
Endig J, Unrau L, Sprezyna P, Rading S, Karsak M, Goltz D, et al.
Int J Mol Sci
. 2019 Nov;
20(22).
PMID: 31698731
Myeloid cells are essential for the initiation and termination of innate and adaptive immunity that create homeostasis in the liver. Smad7 is an inhibitor of the transforming growth factor β...
6.
Tolksdorf F, Mikulec J, Geers B, Endig J, Sprezyna P, Heukamp L, et al.
Sci Rep
. 2018 Nov;
8(1):16123.
PMID: 30382149
Interleukin-2 (IL-2) is a key regulator of adaptive immune responses but its regulation is incompletely understood. We previously found that PDL1-dependent signals were pivotal for liver sinusoidal endothelial cell-mediated priming...