Linda Diehl
Overview
Explore the profile of Linda Diehl including associated specialties, affiliations and a list of published articles.
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41
Citations
1064
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Recent Articles
1.
Hagenstein J, Burkhardt S, Sprezyna P, Tasika E, Tiegs G, Diehl L
J Leukoc Biol
. 2024 Mar;
116(1):177-185.
PMID: 38484149
In chronic inflammation, regulatory immune cells, such as regulatory T cells and myeloid-derived suppressor cells, can develop. Local signals in the inflamed tissue, such as cytokines and eicosanoids, but also...
2.
Gewalt T, Diehl L, Meder L
Front Oncol
. 2024 Mar;
14:1373308.
PMID: 38444685
No abstract available.
3.
Genduso S, Freytag V, Schetler D, Kirchner L, Schiecke A, Maar H, et al.
J Hematol Oncol
. 2023 Mar;
16(1):23.
PMID: 36932441
Background: The immunological composition of the tumor microenvironment has a decisive influence on the biological course of cancer and is therefore of profound clinical relevance. In this study, we analyzed...
4.
Geers B, Hagenstein J, Endig J, Ulrich H, Fleig L, Sprezyna P, et al.
Cells
. 2022 Sep;
11(17).
PMID: 36078047
Interleukin-2 is central to the induction and maintenance of both natural (nT) and induced Foxp3-expressing regulatory T cells (iT). Thus, signals that modulate IL-2 availability may, in turn, also influence...
5.
Linke A, Cicek H, Muller A, Meyer-Schwesinger C, Melderis S, Wiech T, et al.
Cells
. 2022 May;
11(9).
PMID: 35563816
Immune-mediated glomerular diseases are characterized by infiltration of T cells, which accumulate in the periglomerular space and tubulointerstitium in close contact to proximal and distal tubuli. Recent studies described proximal...
6.
Unrau L, Endig J, Goltz D, Sprezyna P, Ulrich H, Hagenstein J, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769006
Myeloid cells play an essential role in the maintenance of liver homeostasis, as well as the initiation and termination of innate and adaptive immune responses. In chronic hepatic inflammation, the...
7.
Meder L, Florin A, Ozretic L, Nill M, Koker M, Meemboor S, et al.
Pathol Oncol Res
. 2021 Jul;
27:596522.
PMID: 34257546
Abrogation of Notch signaling, which is pivotal for lung development and pulmonary epithelial cell fate decisions was shown to be involved in the aggressiveness and the differentiation of lung carcinomas....
8.
Jori B, Schatz S, Kaller L, Kah B, Roeper J, Ramdani H, et al.
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34201252
Since 2009, several first, second, and third generation tyrosine kinase inhibitors (TKI) have been approved for targeted treatment of mutated metastatic non-small lung cancer (NSCLC). A vast majority of patients...
9.
Horst A, Kumashie K, Neumann K, Diehl L, Tiegs G
Cell Mol Immunol
. 2020 Oct;
18(1):92-111.
PMID: 33110250
The liver is an important immunological organ that controls systemic tolerance. The liver harbors professional and unconventional antigen-presenting cells that are crucial for tolerance induction and maintenance. Orchestrating the immune...
10.
Schatz S, Falk M, Jori B, Ramdani H, Schmidt S, Willing E, et al.
Cancers (Basel)
. 2020 Jul;
12(6).
PMID: 32599951
In recent years, Non-small cell lung cancer (NSCLC) has evolved into a prime example for precision oncology with multiple FDA-approved "precision" drugs. For the majority of NSCLC lacking targetable genetic...