Paula M Oliver
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Explore the profile of Paula M Oliver including associated specialties, affiliations and a list of published articles.
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36
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972
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Recent Articles
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Dybas J, OLeary C, Ding H, Spruce L, Seeholzer S, Oliver P
Nat Immunol
. 2019 May;
20(6):747-755.
PMID: 31061531
Despite gathering evidence that ubiquitylation can direct non-degradative outcomes, most investigations of ubiquitylation in T cells have focused on degradation. Here, we integrated proteomic and transcriptomic datasets from primary mouse...
13.
Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G
Cell Rep
. 2019 Mar;
26(12):3298-3312.e4.
PMID: 30893602
Commissural axons initially respond to attractive signals at the midline, but once they cross, they become sensitive to repulsive cues. This switch prevents axons from re-entering the midline. In insects...
14.
Layman A, Deng G, OLeary C, Tadros S, Thomas R, Dybas J, et al.
Nat Commun
. 2017 Jun;
8:15677.
PMID: 28580955
Foxp3 T regulatory (T) cells suppress immune cell activation and establish normal immune homeostasis. How T cells maintain their identity is not completely understood. Here we show that Ndfip1, a...
15.
Moser E, Field N, Oliver P
Cell Mol Immunol
. 2017 Mar;
15(5):480-492.
PMID: 28260794
The ubiquitin ligase, Itch, is required to prevent autoinflammatory disease in mice and humans. Itch-deficient mice develop lethal pulmonary inflammation characterized by the production of Th2 cytokines (for example, interleukin-4...
16.
Layman A, Sprout S, Phillips D, Oliver P
Sci Rep
. 2017 Jan;
7:39649.
PMID: 28051111
While Th17 cells can protect against colonization by pathogenic organisms, they also have the potential to become pathogenic and promote autoimmune and inflammatory diseases. Mechanisms that control their pathogenic potential...
17.
Layman A, Oliver P
J Immunol
. 2016 May;
196(10):3975-82.
PMID: 27183634
The human body is exposed to potentially pathogenic microorganisms at barrier sites such as the skin, lungs, and gastrointestinal tract. To mount an effective response against these pathogens, the immune...
18.
OLeary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al.
Nat Commun
. 2016 Apr;
7:11226.
PMID: 27088444
Nedd4 family E3 ubiquitin ligases have been shown to restrict T-cell function and impact T-cell differentiation. We show here that Ndfip1 and Ndfip2, activators of Nedd4 family ligases, together limit...
19.
Liu Y, OLeary C, Wang L, Bhatti T, Dai N, Kapoor V, et al.
Oncoimmunology
. 2016 Mar;
5(1):e1061175.
PMID: 26942073
Neutrophils are important innate immune cells involved in microbial clearance at the sites of infection. However, their role in cancer development is unclear. We hypothesized that neutrophils mediate antitumor effects...
20.
OLeary C, Lewis E, Oliver P
Front Immunol
. 2016 Jan;
6:618.
PMID: 26732666
T cell receptor (TCR) signaling must be precisely tuned to limit collateral damage and prevent reactivity to self, while still allowing robust protective immune responses that control pathogen invasion. One...