Paul W Dempsey
Overview
Explore the profile of Paul W Dempsey including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
1345
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0
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Recent Articles
1.
Dempsey P, Sandu C, Gonzalezirias R, Hantula S, Covarrubias-Zambrano O, Bossmann S, et al.
Commun Med (Lond)
. 2024 Mar;
4(1):37.
PMID: 38443590
Background: Lung cancer is associated with the greatest cancer mortality as it typically presents with incurable distributed disease. Biomarkers relevant to risk assessment for the detection of lung cancer continue...
2.
Hodara E, Morrison G, Cunha A, Zainfeld D, Xu T, Xu Y, et al.
JCI Insight
. 2019 Feb;
4(5).
PMID: 30702443
Molecular profiling of prostate cancer with liquid biopsies, such as circulating tumor cells (CTCs) and cell-free nucleic acid analysis, yields informative yet distinct data sets. Additional insights may be gained...
3.
Bingham C, Fernandez S, Fittipaldi P, Dempsey P, Ruth K, Cristofanilli M, et al.
Breast Cancer Res Treat
. 2017 Mar;
163(2):219-230.
PMID: 28271309
Purpose: The molecular characterization of circulating tumor cells (CTCs) is critical to identify the key drivers of cancer metastasis and devising therapeutic approaches, particularly for inflammatory breast cancer (IBC) which...
4.
Strauss W, Carter C, Simmons J, Klem E, Goodman N, Vahidi B, et al.
Oncotarget
. 2016 Apr;
7(18):26724-38.
PMID: 27049831
Targeted cancer therapeutics are promised to have a major impact on cancer treatment and survival. Successful application of these novel treatments requires a molecular definition of a patient's disease typically...
5.
Winer-Jones J, Vahidi B, Arquilevich N, Fang C, Ferguson S, Harkins D, et al.
PLoS One
. 2014 Feb;
9(1):e86717.
PMID: 24489774
Background: Contemporary cancer diagnostics are becoming increasing reliant upon sophisticated new molecular methods for analyzing genetic information. Limiting the scope of these new technologies is the lack of adequate solid...
6.
7.
Pietras E, Miller L, Johnson C, OConnell R, Dempsey P, Cheng G
Cell Res
. 2011 Apr;
21(7):1068-79.
PMID: 21467996
Monocytes are mobilized to sites of infection via interaction between the chemokine MCP-1 and its receptor, CCR2, at which point they differentiate into macrophages that mediate potent antimicrobial effects. In...
8.
Razani B, Zarnegar B, Ytterberg A, Shiba T, Dempsey P, Ware C, et al.
Sci Signal
. 2010 May;
3(123):ra41.
PMID: 20501937
Canonical and noncanonical nuclear factor kappaB (NF-kappaB) signaling are the two basic pathways responsible for the release of NF-kappaB dimers from their inhibitors. Enhanced NF-kappaB signaling leads to inflammatory and...
9.
Chin A, Miyahira A, Covarrubias A, Teague J, Guo B, Dempsey P, et al.
Cancer Res
. 2010 Mar;
70(7):2595-603.
PMID: 20233880
Inflammation has increasingly been recognized as a critical component influencing tumor growth. Recent reports have revealed conflicting evidence for the role of Toll-like receptors (TLR) in modulating tumorigenesis. In our...
10.
Liu P, Schenk M, Walker V, Dempsey P, Kanchanapoomi M, Wheelwright M, et al.
PLoS One
. 2009 Jun;
4(6):e5810.
PMID: 19503839
Antimicrobial effector mechanisms are central to the function of the innate immune response in host defense against microbial pathogens. In humans, activation of Toll-like receptor 2/1 (TLR2/1) on monocytes induces...